Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace+46 more
core +1 more source
Phospholipid directed motility of surface‐motile bacteria [PDF]
Summary Myxococcus xanthus is a surface‐motile bacterium that has adapted at least one chemosensory system to allow directed movement towards the slowly diffusible lipid phosphatidylethanolamine (PE). The Dif chemosensory pathway is remarkable because it has at least three inputs coupled to outputs that control extracellular matrix (ECM) production and
Lawrence J. Shimkets, Pamela J. Bonner
openaire +3 more sources
Flagella-Driven Motility of Bacteria
The bacterial flagellum is a helical filamentous organelle responsible for motility. In bacterial species possessing flagella at the cell exterior, the long helical flagellar filament acts as a molecular screw to generate thrust.
Shuichi Nakamura, T. Minamino
semanticscholar +1 more source
Fractal aggregation of active particles [PDF]
We study active run-and-tumble particles with an additional two-state internal variable characterizing their motile or non-motile state. Motile particles change irreversibly into non-motile ones upon collision with a non-motile particle. The system evolves towards an absorbing state where all particles are non-motile.
arxiv +1 more source
Assessment of cellular proliferation, death and senescence in a model of steatosis in vitro
Introduction and objectives: Hepatocyte cell culture in steatogenic medium is a useful, reproducible tool. During NAFLD, cells undergo processes in response to the steatogenic input. Here we aimed to study cellular proliferation, death, and senescence in
A Campos-Espinosa+2 more
doaj
Normal Pursuit-System Limitations— First Discovered in Infantile Nystagmus Syndrome
Infantile nystagmus syndrome (INS) patients occasionally have impaired pursuit. Model and patient data identified relative timing between target motion initiation and INS-waveform saccades as the cause. We used a new stimulus, the “step-pause-ramp” (SPR),
Louis F. Dell’Osso, Jonathan B. Jacobs
doaj +1 more source
Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Althaus, Rupert+9 more
core +1 more source
Self-organization of swimmers drives long-range fluid transport in bacterial colonies [PDF]
Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations in microbial communities are believed to be important to dispersal, quest for food, and material transport. However,
arxiv +1 more source
The Pathophysiology of Chronic Constipation
Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent stools, difficult stool passage or both. The common approach to the pathophysiology of constipation groups the disorder into primary and secondary causes. Primary
Christopher N Andrews, Martin Storr
doaj +1 more source
Cryo-EM structure of the folded-back state of human β-cardiac myosin
To save energy and precisely regulate cardiac contractility, cardiac muscle myosin heads are sequestered in an ‘off’ state that can be converted to an ‘on’ state when exertion is increased. The ‘off’ state is equated with a folded-back structure known as
Alessandro Grinzato+10 more
doaj +1 more source