Results 61 to 70 of about 843,128 (402)

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

open access: yes, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace   +46 more
core   +1 more source

Phospholipid directed motility of surface‐motile bacteria [PDF]

open access: yesMolecular Microbiology, 2006
Summary Myxococcus xanthus is a surface‐motile bacterium that has adapted at least one chemosensory system to allow directed movement towards the slowly diffusible lipid phosphatidylethanolamine (PE). The Dif chemosensory pathway is remarkable because it has at least three inputs coupled to outputs that control extracellular matrix (ECM) production and
Lawrence J. Shimkets, Pamela J. Bonner
openaire   +3 more sources

Flagella-Driven Motility of Bacteria

open access: yesBiomolecules, 2019
The bacterial flagellum is a helical filamentous organelle responsible for motility. In bacterial species possessing flagella at the cell exterior, the long helical flagellar filament acts as a molecular screw to generate thrust.
Shuichi Nakamura, T. Minamino
semanticscholar   +1 more source

Fractal aggregation of active particles [PDF]

open access: yesPhys. Rev. E 98, 052603 (2018), 2018
We study active run-and-tumble particles with an additional two-state internal variable characterizing their motile or non-motile state. Motile particles change irreversibly into non-motile ones upon collision with a non-motile particle. The system evolves towards an absorbing state where all particles are non-motile.
arxiv   +1 more source

Assessment of cellular proliferation, death and senescence in a model of steatosis in vitro

open access: yesAnnals of Hepatology, 2022
Introduction and objectives: Hepatocyte cell culture in steatogenic medium is a useful, reproducible tool. During NAFLD, cells undergo processes in response to the steatogenic input. Here we aimed to study cellular proliferation, death, and senescence in
A Campos-Espinosa   +2 more
doaj  

Normal Pursuit-System Limitations— First Discovered in Infantile Nystagmus Syndrome

open access: yesJournal of Eye Movement Research, 2013
Infantile nystagmus syndrome (INS) patients occasionally have impaired pursuit. Model and patient data identified relative timing between target motion initiation and INS-waveform saccades as the cause. We used a new stimulus, the “step-pause-ramp” (SPR),
Louis F. Dell’Osso, Jonathan B. Jacobs
doaj   +1 more source

Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]

open access: yes, 2009
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Althaus, Rupert   +9 more
core   +1 more source

Self-organization of swimmers drives long-range fluid transport in bacterial colonies [PDF]

open access: yes, 2019
Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations in microbial communities are believed to be important to dispersal, quest for food, and material transport. However,
arxiv   +1 more source

The Pathophysiology of Chronic Constipation

open access: yesCanadian Journal of Gastroenterology, 2011
Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent stools, difficult stool passage or both. The common approach to the pathophysiology of constipation groups the disorder into primary and secondary causes. Primary
Christopher N Andrews, Martin Storr
doaj   +1 more source

Cryo-EM structure of the folded-back state of human β-cardiac myosin

open access: yesNature Communications, 2023
To save energy and precisely regulate cardiac contractility, cardiac muscle myosin heads are sequestered in an ‘off’ state that can be converted to an ‘on’ state when exertion is increased. The ‘off’ state is equated with a folded-back structure known as
Alessandro Grinzato   +10 more
doaj   +1 more source

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