Results 61 to 70 of about 731,626 (335)

Correlations between the clinical characteristics of diabetic trochlear nerve palsy and diplopia severity

BMC Ophthalmology
Importance Few literatures reported the clinical characteristics of diabetic trochlear nerve palsy, including demographic characteristics, involvement between both eyes, time of symptom onset, duration of diabetes, etc. Whether there is relevance between
Zhaowen Xue, Tianxiang Cao, Xuemei Li, Deyu Hu, Yuan Li, Lingyun Zhou   +5 more
doaj   +1 more source

The myosin X motor is optimized for movement on actin bundles

Nature Communications, 2016
Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is ...
Virginie Ropars, Zhaohui Yang, Tatiana Isabet, Florian Blanc, Kaifeng Zhou, Tianming Lin, Xiaoyan Liu, Pascale Hissier, Frédéric Samazan, Béatrice Amigues, Eric D. Yang, Hyokeun Park, Olena Pylypenko, Marco Cecchini, Charles V. Sindelar, H. Lee Sweeney, Anne Houdusse   +16 more
doaj   +1 more source

P-27 CELLULAR EFFECTS OF IN VITRO LIPID OVERLOAD ON HEPATIC STELLATE CELLS AND HEPATOCYTES.

Annals of Hepatology, 2023
Introduction and Objectives: Hepatic cells undergo different processes in response to the steatogenic input of MAFLD. Hepatic cell culture in steatogenic medium is a useful, reproducible tool intended to elucidate these pathogenic mechanisms.
Adriana Campos-Espinosa, José Luis Pérez-Hernández, Gabriela Gutiérrez-Reyes, Carolina Guzmán   +3 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

STATINS, MYOPATHY AND PHYSICAL ACTIVITY

Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2018
Background: Cholesterol-lowering therapy (statins), associated with lifestyle modifications, have an important role in reducing atherosclerotic cardiovascular disease (ASCVD) events.
Elena SÎRBU, Șerban GLIGOR
doaj   +1 more source

How bacterial cells and colonies move on solid substrates

, 2019
Many bacteria rely on active cell appendages, such as type IV pili, to move over substrates and interact with neighboring cells. Here, we study the motion of individual cells and bacterial colonies, mediated by the collective interactions of multiple ...
Pönisch, Wolfram, Weber, Christoph A., Zaburdaev, Vasily   +2 more
core   +1 more source

Mechanics and polarity in cell motility [PDF]

, 2016
The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in magnitude and ...
Ambrosi, Davide, Zanzottera, Anna
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Cryo-EM structure of the folded-back state of human β-cardiac myosin

Nature Communications, 2023
To save energy and precisely regulate cardiac contractility, cardiac muscle myosin heads are sequestered in an ‘off’ state that can be converted to an ‘on’ state when exertion is increased. The ‘off’ state is equated with a folded-back structure known as
Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M. Ruppel, James A. Spudich, Anne Houdusse, Julien Robert-Paganin   +10 more
doaj   +1 more source

Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements. [PDF]

, 2018
Syntaphilin (SNPH) inhibits the movement of mitochondria in tumor cells, preventing their accumulation at the cortical cytoskeleton and limiting the bioenergetics of cell motility and invasion. Although this may suppress metastasis, the regulation of the
Agarwal, Ekta, Altieri, Dario C., Bryant, Kelly G., Caino, M. Cecilia, Cohen, Andrew R., Gabrilovich, Dmitry I., Kim, Eui Tae, Kossenkov, Andrew V., Languino, Lucia R., Seo, Jae Ho, Speicher, David W., Tang, Hsin-Yao   +11 more
core   +1 more source