Results 71 to 80 of about 730,542 (336)

Automated single-cell motility analysis on a chip using lensfree microscopy. [PDF]

open access: yes, 2014
Quantitative cell motility studies are necessary for understanding biophysical processes, developing models for cell locomotion and for drug discovery.
Di Carlo, Dino   +6 more
core   +1 more source

Esophageal High Pressure Zones: Effect of Perisophageal Structures on Esophageal Manometric Recording

open access: yesCanadian Journal of Gastroenterology, 1994
During the course of esophageal motility studies, short zones of elevated esophageal baseline pressure are occasionally noticed. The aim of this study is to determine their frequency and their cause. Among 77 consecutive esophageal manometries (group 1),
G Bédard, A Pellicano, R Ste-Marie
doaj   +1 more source

Automatic diagnosis of extraocular muscle palsy based on machine learning and diplopia images [PDF]

open access: yesInternational Journal of Ophthalmology
AIM: To develop different machine learning models to train and test diplopia images and data generated by the computerized diplopia test. METHODS: Diplopia images and data generated by computerized diplopia tests, along with patient medical records, were
Xiao-Lu Jin   +3 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

A mathematical model quantifies proliferation and motility effects of TGF--$\beta$ on cancer cells [PDF]

open access: yes, 2008
Transforming growth factor (TGF) $\beta$ is known to have properties of both a tumor suppressor and a tumor promoter. While it inhibits cell proliferation, it also increases cell motility and decreases cell--cell adhesion.
Arteaga, Carlos L.   +6 more
core   +3 more sources

Gastrointestinal motility revisited: The wireless motility capsule [PDF]

open access: yesUnited European Gastroenterology Journal, 2013
IntroductionThe wireless motility capsule (WMC) is a novel ambulatory technology that concurrently measures intraluminal pH, temperature, and pressure as it traverses the gastrointestinal tract.ObjectivesWe aim to provide a concise summary of the WMC, detailing the procedure for its administration and the parameters it records.
Anthony Hobson   +2 more
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Effects of caerulein on the gastric motility of rats. [PDF]

open access: yes, 1985
The effects of caerulein on gastric motility in urethane-anesthetized rats were studied. Caerulein administered into the lateral cerebral ventricle (i.c.v.) and jugular vein (i.v.) caused predominantly an inhibitory effect on gastric motility but ...
Jin, Ze-Zhong   +2 more
core   +1 more source

Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction

open access: yesNature Communications
Inherited cardiomyopathies are common cardiac diseases worldwide, leading in the late stage to heart failure and death. The most promising treatments against these diseases are small molecules directly modulating the force produced by β-cardiac myosin ...
Daniel Auguin   +8 more
doaj   +1 more source

The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity

open access: yesNature Communications, 2021
Plasmodium falciparum moves by an atypical process called gliding motility which comprises of atypical myosin A (PfMyoA) and filaments of the dynamic and divergent PfActin-1 (PfAct1).
Julien Robert-Paganin   +11 more
doaj   +1 more source

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