Results 101 to 110 of about 23,735,145 (303)

Novel near E-Field Topography Sensor for Human–Machine Interfacing in Robotic Applications

Sensors
This work investigates a new sensing technology for use in robotic human–machine interface (HMI) applications. The proposed method uses near E-field sensing to measure small changes in the limb surface topography due to muscle actuation over time.
Dariusz J. Skoraczynski, Chao Chen
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Specifications and functional impact of a self-triggered grasp neuroprosthesis developed to restore prehension in hemiparetic post-stroke subjects

BioMedical Engineering OnLine
Background Stroke is the leading cause of acquired motor deficiencies in adults. Restoring prehension abilities is challenging for individuals who have not recovered active hand opening capacities after their rehabilitation.
R. Le Guillou, J. Froger, M. Morin, M. Couderc, C. Cormier, C. Azevedo-Coste, D. Gasq   +6 more
doaj   +1 more source

Long-term robot-assisted gait training in patients with cerebral palsy: meaningful changes in gait parameters require time

Frontiers in Human Neuroscience
IntroductionRobot-assisted gait training (RAGT) is increasingly used in children with cerebral palsy (CP), but evidence regarding the timing and persistence of meaningful changes in gait remains limited.
Paweł Chmara, Sabina Brazevič, Marek Jóźwiak, Faustyna Manikowska   +3 more
doaj   +1 more source

Sagittal Plane Trunk Tilt Is Associated With Upper Extremity Joint Moments and Ball Velocity in Collegiate Baseball Pitchers

Orthopaedic Journal of Sports Medicine, 2018
Background: The trunk is a major contributor to the kinetic chain during baseball pitching by helping to transfer energy from the lower limbs to produce the desired ball speed. However, most of the research detailing the trunk’s contribution to the pitch
Matthew J. Solomito PhD, Erin J. Garibay MS, Carl W. Nissen MD   +2 more
doaj   +1 more source

Human motion analysis.

, 2007
In recent years, human motion analysis increasingly becomes one of the most active research areas in computer vision, which is motivated by a wide spectrum of promising applications such as intelligent visual surveillance, content-based video retrieval, human-computer interaction, and so on.
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

LLM-Assisted Interpretation of Kinematic Gait Data in Children with Cerebral Palsy: A Pilot Study on Gait Deviation Detection and Surgical Group Recommendations

Bioengineering
Three-dimensional instrumented gait analysis is widely used to guide surgical decision-making in children with cerebral palsy (CP), but its interpretation is time-consuming and prone to inter-rater variability.
Mehrdad Davoudi, Jacqueline Romkes, Michèle Widmer, Chris Easthope Awai, Elke Viehweger   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source