Results 111 to 120 of about 2,908,066 (284)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Implementing Spatial Intelligence-Based Respond Method in the Physics Instruction to Improve Physics Learning Outcomes on the Lesson Subject of Straight Motion of the Tenth Grade Students of SMA N 1 Jogolagan in the First Semester [PDF]

, 2010
This study aims at determining influences of the spatial intelligence-based respond method towards physics learning outcomes on the subject of straight motion of the students of Grade X of SMA N 1 Jogonalan. This research also aims at determining whether
WINARKO ARGI PRAMONO, -
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Investigating the Reliability of the Knee Joint Flexors and Extensors Muscles Length Tests Modified to Meet the Requirements of Scientific Research [PDF]

Journal of Rehabilitation
Objective This study evaluates the intra- and inter-rater reliability of modified versions of the widely used clinical tests for assessing knee flexor and knee extensor muscle length.
Rafał Gnat, Anna Gogola, Agnieszka Polaczek, Piotr Woźniak, Tomasz Wolny   +4 more
doaj  

A New Characterization of Fine Scale Diffusion on the Cell Membrane [PDF]

, 2015
We use a large single particle tracking data set to analyze the short time and small spatial scale motion of quantum dots labeling proteins in cell membranes.
Espinoza, Flor A., Steinberg, Stanly L.
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Human Motion Analysis

, 2007
In recent years, human motion analysis increasingly becomes one of the most active research areas in computer vision, which is motivated by a wide spectrum of promising applications such as intelligent visual surveillance, content-based video retrieval, human-computer interaction, and so on.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical Gait Evaluation with Neuromuscular Impairments (Clinical GENI) for spastic cerebral palsy

Frontiers in Human Neuroscience
BackgroundGait abnormalities in spastic cerebral palsy (CP) result from four primary neuromuscular impairments: muscle weakness, short muscle-relative-to-skeletal-length, muscle spasticity, and impaired selective motor control.
Kylie Clewes, Yiwen Dong, Yiwen Dong, Yiwen Dong, Mary Meyer, Evan Lowe, Kornél Schadl, Kornél Schadl, Jessica Rose, Jessica Rose   +9 more
doaj   +1 more source