Results 61 to 70 of about 2,908,066 (284)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Aggregation Periods Influence Step Count Error in Low-Power Wearables
SensorsWearable sensors are increasingly used to monitor physical activity, yet low-power devices often rely on data aggregation to conserve battery life, potentially impacting measurement accuracy.
Sydney Lundell, Kenton R. Kaufman
doaj +1 more source
Stability Control of a Biped Robot on a Dynamic Platform Based on Hybrid Reinforcement Learning
Sensors, 2020 In this work, we introduced a novel hybrid reinforcement learning scheme to balance a biped robot (NAO) on an oscillating platform, where the rotation of the platform is considered as the external disturbance to the robot. The platform had two degrees of
Ao Xi, Chao Chen
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Mechanical Method for Rapid Determination of Step Count Sensor Settings
BioengineeringWith the increased push for personalized medicine, researchers and clinicians have begun exploring the use of wearable sensors to track patient activity.
Sydney Lundell, Kenton R. Kaufman
doaj +1 more source
A qualitative approach to the identification, visualisation and interpretation of repetitive motion patterns in groups of moving point objects [PDF]
, 2015 Discovering repetitive patterns is important in a wide range of research areas, such as bioinformatics and human movement analysis. This study puts forward a new methodology to identify, visualise and interpret repetitive motion patterns in groups of ...
Chavoshi, Seyed Hossein +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Biomedical Human Kinetics, 2023 Study aim: The aim of the study was to evaluate asymmetry of activation of lateral abdominal muscles (LAM) in response to neurodevelopmental traction technique in children with pelvic asymmetry.
Polaczek Agnieszka, Szlachta Grzegorz
doaj +1 more source