Results 81 to 90 of about 17,115,391 (356)

Ultra-Long, Minor-Diameter, Untethered Growing Continuum Robot via Tip Actuation and Steering

Machines
Continuum robots with outstanding compliance, dexterity, and lean bodies are successfully applied in medicine, aerospace engineering, the nuclear industry, rescue operations, construction, service, and manipulation.
Pan Zhou, Zhaoyi Lin, Lang Zhou, Haili Li, Michael Basin, Jiantao Yao   +5 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Adaptive Coordinated Motion Control for Swarm Robotics Based on Brain Storm Optimization [PDF]

, 2021
Jian Yang, Yuhui Shi
openalex   +1 more source

Differences in Motor Development between Preterm Infants and Full-Term Preschool Children

Children
Although advances in obstetric and neonatal care have improved the survival of preterm infants, many studies document the increased risk of motor and sensory neurodevelopmental abnormalities that can hinder school progress.
Alicia Cuesta-Gómez, Pilar Fernández-González, María Carratalá-Tejada, Inmaculada Aguilar-Bejines   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Comprehensive analysis of suspending force for improved bearingless switched reluctance motor with permanent magnets in stator yoke

CES Transactions on Electrical Machines and Systems, 2018
Different from conventional switched reluctance motor(SRM), bearingless SRM not only provides torque but also supplies levitation force for free-friction of rotor.
Fangxu Li, Huijun Wang, Fengge Zhang, He Zhang   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

High Precision Cnc Motion Control [PDF]

, 2004
Bu tezde yüksek doğruluklu CNC hareket kontrolü için bir elektrik sürücü sistemi tasarlanması amaçlamıştır. Modern elektrik motor sürücülerinin üzerinde yapılan araştırmalar; motor sürücülerinin akım kontrollü voltaj kaynağı ve bir veya birden fazla mikroişlemci/mikrodenetleyici ya da sayısal sinyal işlemcilere (DSPs) sahip güçlü hareket ...
openaire   +2 more sources