Results 41 to 50 of about 119,993 (264)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Efficient and Asymptotically Optimal Vehicle Motion Planning With Stochastic Template-Based RRT*
IEEE AccessKinodynamic motion planning plays a vital role in robotics, particularly in autonomous driving, where planned trajectories must satisfy kinematic and dynamic constraints while ensuring both safety and efficiency.
Shaoyu Yang, Masamichi Shimosaka
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A Hybrid Motion Planning Algorithm for Multi-Mobile Robot Formation Planning
Robotics, 2023 This paper addresses the problem of relative position-based formation planning for a leader–follower multi-robot setup, where the robots adjust the formation parameters, such as size and three-dimensional orientation, to avoid collisions and progress ...
Haojie Chen +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A Minimum-Time Motion Online Planning Method for Underactuated Overhead Crane Systems
IEEE Access, 2019 In this paper, a minimum-time motion online planning (MTMOLP) method is proposed for underactuated overhead crane systems within both safety and physical constraints.
Fan Li, Chenghui Zhang, Bo Sun
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Aerospace, 2022 During the on-orbit operation task of the space manipulator, some specific scenarios require strict constraints on both the position and orientation of the end-effector, such as refueling and auxiliary docking.
Yinkang Li +5 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Kicking Motion Planning of Humanoid Robot Based on B-Spline Curves
Journal of Applied Science and Engineering, 2022 Effective and powerful kicking motion is a key prerequisite for humanoid robots to play robot soccer. However, the kicking motion is a complex motion.
Chih-Cheng Liu +3 more
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