Results 61 to 70 of about 11,193,681 (316)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A Review of Research Progress on Cables and Towed Objects of the Ocean Engineering Towing System
Journal of Marine Science and EngineeringTowing operations are widely applied in various fields such as maritime accident rescue, assisting large vessels entering and exiting ports, and transporting large ocean platforms. Tugboats and the towed objects form a complex multi-body system connected
Kefu Qi +4 more
doaj +1 more source
Journal of Hebei University of Science and Technology, 2015 The environmental loads such as wind, wave, flow onto drilling rig and mooring system of the HaiYangShiYou 981 are analyzed according to the actual working condition in South China Sea. The Haiyang Shiyou 981 drilling rig is chosen as the research object
Qiaolei SUN +5 more
doaj +1 more source
, 2017 In the present study, output‐only modal dynamic identification and monitoring of building properties is attempted successfully by processing real earthquake‐induced structural response signals.
Fabio Pioldi, R. Ferrari, E. Rizzi
semanticscholar +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Analysis on ice resistance and ice response of ships sailing in brash ice
Zhongguo Jianchuan Yanjiu, 2018 [Objectives] In order to explore the interaction between a hull and crushed ice, [Methods] a discrete element model is combined with Euler multiphase flow.
WANG Chao, FENG Zhen, LI Xing, LI Peng
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
南方能源建设[Objective] This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.
Wanqi WANG +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Engineering Applications of Computational Fluid MechanicsWith the expansion of mariculture into offshore areas, analysing the hydrodynamic characteristics of net cage structures under wave action has become increasingly important.
Sen-Qi Cui, Chun-Wei Bi
doaj +1 more source