Results 91 to 100 of about 454,439 (370)

Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice [PDF]

open access: yes, 2014
Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also ...
Colettis, Natalia Claudia   +8 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Comparison of two combinations of anaesthetic agents with and without ketamine for motor evoked potential during spine surgeries

open access: yesThe Indian Anaesthetists' Forum, 2017
Background: Anesthetic agents cause a dose-dependent effect on motor-evoked potentials (MEPs). We conducted a study to find whether addition of ketamine to the combination of propofol–fentanyl–dexmedetomidine has an effect on MEP monitoring and ...
Parashuram Chauhan   +3 more
doaj   +1 more source

The task complexity and Extraversion: an ERP study [PDF]

open access: yes, 2007
Trying to prove the validity of Eysenck’s theories for the biological basis of personality many data for the differences between extraverts and introverts were collected.
Georgiev, Stiliyan   +2 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Multimodal imaging of human brain activity: rational, biophysical aspects and modes of integration [PDF]

open access: yes, 2009
Until relatively recently the vast majority of imaging and electrophysiological studies of human brain activity have relied on single-modality measurements usually correlated with readily observable or experimentally modified behavioural or brain state ...
Astolfi, L.   +6 more
core   +3 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Predictive modeling of TMS-evoked responses: Unraveling instantaneous excitability states

open access: yesNeuroImage
Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) and electromyography (EMG) provides a unique window into instantaneous cortical and corticospinal excitability states. We investigated 50 healthy participants to determine
Oskari Ahola   +12 more
doaj   +1 more source

Brain Activity Underlying Muscle Relaxation

open access: yesFrontiers in Physiology, 2019
Fine motor control of not only muscle contraction but also muscle relaxation is required for appropriate movements in both daily life and sports. Movement disorders such as Parkinson’s disease and dystonia are often characterized by deficits of muscle ...
Kouki Kato   +3 more
doaj   +1 more source

A Novel Latency Estimation Algorithm of Motor Evoked Potential Signals

open access: yesIEEE Access, 2020
Evaluation of motor evoked potential (MEP) signals elicited by transcranial magnetic stimulation (TMS) over the motor cortex provide a measure of cortico-motor excitability at the time of stimulation.
Josko Soda   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy