Results 61 to 70 of about 9,598,950 (291)

Safety of sugammadex muscle relaxation reversal during spinal surgery with motor evoked potential monitoring [PDF]

Jichu yixue yu linchuang
Objective To explore the effect of sugammadex on safety indicators such as body movement, choking, peak airway pressure during spinal surgery with motor evoked potential monitoring.
MA Bo, JIAN Minyu, JING Longnian, WANG Chengwei, LIU Haiyang, HAN Ruquan
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Threshold variation of transcranial motor evoked potential with threshold criterion in frontotemporal craniotomy

Clinical Neurophysiology Practice, 2019
Objective: Motor threshold usually varies in the intraoperative motor evoked potential (MEP) by transcranial evoked stimulation (TES). This study investigated the degree of change in the motor threshold before and after surgery in TES-MEP monitoring with
Kohei Kanaya, Tetsuya Goto, Tetsuyoshi Horiuchi, Kazuhiro Hongo   +3 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Illustrative motor evoked potential.

, 2019
Single-subject data showing an averaged trace of electromyographic (EMG) activity in the first dorsal interosseous (FDI) muscle during relaxation. The arrow shows the timing of single-pulse transcranial magnetic stimulation (TMS) delivered over the ...
Alex Dilena (7252058), Carolyn Berryman (7252061), Gabrielle Todd (283931), Tasha R. Stanton (7243298), Ebonie Rio (5103188)   +4 more
core   +1 more source

Muscarinic acetylcholine activity modulates cortical silent period, but not motor evoked potentials, during muscle contractions

, 2023
This study used transcranial magnetic stimulation (TMS) to determine if muscarinic receptor blockade affects muscle responses during voluntary contractions.
Kavanagh, Justin J, Dempsey, Lisa M
core   +1 more source

Limitation of Intraoperative Transcranial Electrical Stimulation-Motor Evoked Potential Monitoring During Brain Tumor Resection Adjacent to the Primary Motor Cortex [PDF]

Annals of Rehabilitation Medicine, 2018
Transcranial electrical stimulation-motor evoked potential (TES-MEP) is a valuable intraoperative monitoring technique during brain tumor surgery. However, TES can stimulate deep subcortical areas located far from the motor cortex.
Hui Jae Do, Han Gil Seo, Byung-Mo Oh, Chul-Kee Park, Jin Wook Kim, Young Doo Choi, Seung Hak Lee   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Predictive modeling of TMS-evoked responses: Unraveling instantaneous excitability states

NeuroImage
Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) and electromyography (EMG) provides a unique window into instantaneous cortical and corticospinal excitability states. We investigated 50 healthy participants to determine
Oskari Ahola, Lisa Haxel, Maria Ermolova, Dania Humaidan, Tuomas P. Mutanen, Mikael Laine, Matilda Makkonen, Elena Ukharova, Timo Roine, Pantelis Lioumis, Roberto Guidotti, Risto J. llmoniemi, Ulf Ziemann   +12 more
doaj   +1 more source