Results 61 to 70 of about 2,308,037 (392)
Dissociating motor cortex from the motor
The Journal of Physiology, 2011 Abstract During closed‐loop control of a brain–computer interface, neurons in the primary motor cortex can be intensely active even though the subject may be making no detectable movement or muscle contraction. How can neural activity in the primary motor cortex become dissociated from the movements and muscles of the native limb that it normally ...
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Scientific Reports, 2019 The effectiveness of transcranial direct current stimulation (tDCS) placed over the motor hotspot (thought to represent the primary motor cortex (M1)) to modulate motor network excitability is highly variable.
Stephanie Lefebvre +7 more
doaj +1 more source
The Motor Cortex Communicates with the Kidney [PDF]
The Journal of Neuroscience, 2012 We used retrograde transneuronal transport of rabies virus from the rat kidney to identify the areas of the cerebral cortex that are potential sources of central commands for the neural regulation of this organ. Our results indicate that multiple motor and nonmotor areas of the cerebral cortex contain output neurons that indirectly influence kidney ...
David J, Levinthal, Peter L, Strick
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FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Damage to fronto-parietal networks impairs motor imagery ability after stroke : a voxel-based lesion symptom mapping study [PDF]
, 2016 Background: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ...
Oostra, Kristine M +3 more
core +2 more sources
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Cell Reports, 2018 Summary: Little is known about the organizational and functional connectivity of the corticospinal (CS) circuits that are essential for voluntary movement.
Masaki Ueno +9 more
doaj +1 more source
A longitudinal study of hand motor recovery after sub-acute stroke: a study combined FMRI with diffusion tensor imaging. [PDF]
PLoS ONE, 2013 Previous studies have shown that motor recovery of stroke can be assessed by the cortical activity and the structural integrity of the corticospinal tract (CST), but little is known about the relation between the cortical activity and the structural ...
Wenjuan Wei +11 more
doaj +1 more source
Motor cortex hemodynamic response to goal-oriented and non-goal-oriented tasks in healthy subjects
Frontiers in Neuroscience, 2023 BackgroundMotor disorders are one of the world’s major scourges, and neuromotor rehabilitation is paramount for prevention and monitoring plans. In this scenario, exercises and motor tasks to be performed by patients are crucial to follow and assess ...
Michele Lacerenza +11 more
doaj +1 more source