Results 71 to 80 of about 2,308,037 (392)

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Isolated shoulder weakness as a result of a cortical infarction in the precentral gyrus [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2015
Since its discovery, our understanding of the primary motor cortex has continued to evolve. The presentations of rare, isolated, motor palsies of small muscle groups have heavily contributed to the characterization of the somatotopic representation of ...
Pouya Entezami, John A. Hopper
doaj   +1 more source

Determining a Role for Ventromedial Prefrontal Cortex in Encoding Action-Based Value Signals During Reward-Related Decision Making [PDF]

, 2009
Considerable evidence has emerged to implicate ventromedial prefrontal cortex in encoding expectations of future reward during value-based decision making.
Alan N. Hampton, Balleine, Bechara, Blair, Clark, Cools, Daw, Daw, Deichmann, Dorris, Friston, Hampton, Hampton, Hampton, Hoshi, Jan Gläscher, John P. O'Doherty, Kable, Kennerley, Kim, Kirkpatrick, Knutson, Matsumoto, Matsumoto, Montague, Montague, O'Doherty, O'Doherty, Ostlund, Ostlund, Padoa-Schioppa, Paton, Picard, Platt, Rushworth, Rushworth, Schoenbaum, Schoenbaum, Seo, Seymour, Seymour, Shima, Sohn, Sugrue, Sutton, Thorpe, Tremblay, Tremblay, Tzourio-Mazoyer, Valentin, Volz, von Neumann, Wallis, Walton   +53 more
core   +3 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Low-Intensity Transcranial Ultrasound Stimulation Modulates the Excitability of Motor Cortical Neural Activity by Stimulating the Cerebellum

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Functional connectivity between the cerebellum and the motor cortex is critical for motor function. Low-intensity transcranial ultrasound stimulation (TUS) has been proved to directly activate cerebellar neural activity.
Huifang Yang, Zhe Zhao, Renhao Xu, Jiamin Pei, Jiaqing Yan, Xiangjian Zhang, Hanna Lu, Yi Yuan   +7 more
doaj   +1 more source

Suppressing Systemic Interference in fNIRS Monitoring of the Hemodynamic Cortical Response to Motor Execution and Imagery

Frontiers in Human Neuroscience, 2018
Hemodynamic response to motor execution (ME) and motor imagery (MI) was investigated using functional near-infrared spectroscopy (fNIRS). We used a 31 channel fNIRS system which allows non-invasive monitoring of cerebral oxygenation changes induced by ...
Shijing Wu, Shijing Wu, Jun Li, Lantian Gao, Changshui Chen, Sailing He   +5 more
doaj   +1 more source

Task-free functional MRI in cervical dystonia reveals multi-network changes that partially normalize with botulinum toxin. [PDF]

PLoS ONE, 2013
Cervical dystonia is characterized by involuntary, abnormal movements and postures of the head and neck. Current views on its pathophysiology, such as faulty sensorimotor integration and impaired motor planning, are largely based on studies of focal hand
Cathérine C S Delnooz, Jaco W Pasman, Christian F Beckmann, Bart P C van de Warrenburg   +3 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

How transcranial direct current stimulation can modulate implicit motor sequence learning and consolidation: A brief review

Frontiers in Human Neuroscience, 2016
The purpose of this review is to investigate how transcranial direct current stimulation (tDCS) can modulate implicit motor sequence learning and consolidation.
Branislav eSavic, Branislav eSavic, Beat eMeier, Beat eMeier   +3 more
doaj   +1 more source

A robust role for motor cortex

Frontiers in Neuroscience, 2023
The role of motor cortex in non-primate mammals remains unclear. More than a century of stimulation, anatomical and electrophysiological studies has implicated neural activity in this region with all kinds of movement.
Gonçalo Lopes, Gonçalo Lopes, Gonçalo Lopes, Joana Nogueira, Joana Nogueira, Joana Nogueira, George Dimitriadis, George Dimitriadis, Jorge Aurelio Menendez, Jorge Aurelio Menendez, Jorge Aurelio Menendez, Joseph J. Paton, Adam R. Kampff, Adam R. Kampff, Adam R. Kampff   +14 more
doaj   +1 more source