Results 71 to 80 of about 343,489 (291)

A dissociation between real and simulated movements in Parkinson's disease [PDF]

open access: yes, 2004
Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson's disease ...
Cohen, Henri   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Effect of Phasic Experimental Pain Applied during Motor Preparation or Execution on Motor Performance and Adaptation in a Reaching Task: A Randomized Trial

open access: yesBrain Sciences
Musculoskeletal conditions often involve pain related to specific movements. However, most studies on the impact of experimental pain on motor performance and learning have used tonic pain models.
Laïla Badr   +3 more
doaj   +1 more source

fMRI Investigation of Cortical and Subcortical Networks in the Learning of Abstract and Effector-Specific Representations of Motor Sequences [PDF]

open access: yes, 2006
A visuomotor sequence can be learned as a series of visuo-spatial cues or as a sequence of effector movements. Earlier imaging studies have revealed that a network of brain areas is activated in the course of motor sequence learning.
Bapi, Dr. Raju S.   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Analisa Spektrum Motor Imagery pada Sinyal Aktivitas Otak [PDF]

open access: yes, 2016
Otak merupakan organ vital pada tubuh manusia yang berperan sebagai pusat kendali sistem saraf manusia. Sinyal yang dikeluarkan otak (EEG) mengandung berbagai informasi yang dapat dimanfaatkan pada teknologi BCI. Salah satu informasi yang dapat digunakan
Arifin, A. (Achmad)   +2 more
core  

Short time sports exercise boosts motor imagery patterns: implications of mental practice in rehabilitation programs [PDF]

open access: yes, 2014
Motor imagery (MI) is a commonly used paradigm for the study of motor learning or cognitive aspects of action control. The rationale for using MI training to promote the relearning of motor function arises from research on the functional correlates that ...
Koschutnig, Karl   +3 more
core   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Children with cerebral palsy have altered oscillatory activity in the motor and visual cortices during a knee motor task

open access: yesNeuroImage: Clinical, 2017
The neuroimaging literature on cerebral palsy (CP) has predominantly focused on identifying structural aberrations within the white matter (e.g., fiber track integrity), with very few studies examining neural activity within the key networks that serve ...
Max J. Kurz   +4 more
doaj   +1 more source

EEG signatures of arm isometric exertions in preparation, planning and execution [PDF]

open access: yes, 2014
The electroencephalographic (EEG) activity patterns in humans during motor behaviour provide insight into normal motor control processes and for diagnostic and rehabilitation applications.
Conway, Bernard A   +2 more
core   +1 more source

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