Results 81 to 90 of about 343,489 (291)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Changes in spinal motoneuron excitability during the improvement of fingertip dexterity by actual execution combined with motor imagery practice

Heliyon
Since there is an upper limit to skill improvement through the repetition of actual execution, we examined whether motor imagery could be used in combination with actual execution to maximize motor skill improvement.
Yuki Fukumoto, Marina Todo, Makoto Suzuki, Daisuke Kimura, Toshiaki Suzuki   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Fine Modulation in Network Activation during Motor Execution and Motor Imagery [PDF]

Cerebral Cortex, 2004
Motor imagery, the 'mental rehearsal of motor acts without overt movements', involves either a visual representation (visual imagery, VI) or mental simulation of movement, associated with a kinesthetic feeling (kinetic imagery, KI). Previous brain imaging work suggests that patterns of brain activation differ when comparing execution (E) with either ...
Ana, Solodkin, Petr, Hlustik, E Elinor, Chen, Steven L, Small   +3 more
openaire   +2 more sources

A Deep Learning Approach for Brain Computer Interaction-Motor Execution EEG Signal Classification

IEEE Access, 2021
Recently Noninvasive Electroencephalogram (EEG) systems are gaining much attention. Brain-computer Interface (BCI) systems rely on EEG analysis to identify the mental state of the user, change in cognitive state and response to the events.
Nesma E. Elsayed, Ahmed S. Tolba, Magdi Z. Rashad, Tamer Belal, Shahenda Sarhan   +4 more
doaj   +1 more source

Actual and mental motor preparation and execution: a spatiotemporal ERP study [PDF]

, 2018
Studies evaluating the role of the executive motor system in motor imagery came to a general agreement in favour of the activation of the primary motor area (M1) during imagery, although in reduced proportion as compared to motor execution.
Andrey, Carine, Caldara, Roberto, Deiber, Marie-Pierre, Hauert, Claude-Alain, Michel, Christoph, Thut, Gregor   +5 more
core  

Action observation and motor imagery in performance of complex movements: Evidence from EEG and kinematics analysis [PDF]

, 2015
Motor imagery (MI) and action observation (AO) are considered effective cognitive tools for motor learning, but little work directly compared their cortical activation correlate in relation with subsequent performance.
Comi, Giancarlo, Cursi, Marco, Gatti, Roberto Vincenti, Gonzalez Rosa, Javier Jesús, Leocani, Letizia, Natali, Fabrizio, Tettamanti, Andrea, Velikova, Svetla   +7 more
core   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Executive Functioning, Motor Difficulties, and Developmental Coordination Disorder [PDF]

Developmental Neuropsychology, 2015
The current study assessed a comprehensive range of executive functions (EFs) in children with poor motor skills, comparing profiles of children with a diagnosis of developmental coordination disorder (DCD) and those identified with motor difficulties (MD).
Leonard, H.C., Bernardi, M., Hill, E. L., Henry, L.   +3 more
openaire   +4 more sources

Functional and structural connectivity between the cerebellum and the cortical mirror neuron system: evidence from fMRI and DTI probabilistic tractography

NeuroImage
Studies in humans and monkeys have shown that action observation activates not only cortical areas of the mirror neuron system (MNS) but also the cerebellum and other subcortical structures.
Antonino Errante, Eleonora Sicuri, Cristina Russo, Giuseppe Ciullo, Alessandro Piras, Marzio Gerbella, Leonardo Fogassi   +6 more
doaj   +1 more source