Results 101 to 110 of about 1,014,438 (298)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Instabilities and Oscillations in Isotropic Active Gels [PDF]
, 2010 We present a generic formulation of the continuum elasticity of an isotropic crosslinked active gel. The gel is described by a two-component model consisting of an elastic network coupled frictionally to a permeating fluid.
Ahmadi +47 more
core +4 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A new type of fault diagnosis method of asynchronous motor
Gong-kuang zidonghua, 2014 In view of problem of difficult parameters determination existed in fault diagnosis method of asynchronous motor based on RBF neural network, the paper proposed a fault diagnosis method of asynchronous motor based on RBF neural network optimized by ...
GOU Xijin, XU Jinxia, KONG Lili
doaj +1 more source
Duplication of modules facilitates the evolution of functional specialization [PDF]
, 2000 The evolution of simulated robots with three different architectures is studied. We compared a non-modular feed forward network, a hardwired modular and a duplication-based modular motor control network.
Calabretta, Raffaele +3 more
core +1 more source
Impulsivity Relates to Relative Preservation of Mesolimbic Connectivity in Patients with Parkinson Disease. [PDF]
, 2020 IntroductionThe relationship between Parkinson Disease (PD) pathology, dopamine replacement therapy (DRT), and impulse control disorder (ICD) development is still incompletely understood.
Bari, Ausaf +6 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modelling cytoskeletal traffic: an interplay between passive diffusion and active transport [PDF]
, 2012 We introduce the totally asymmetric exclusion process with Langmuir kinetics (TASEP-LK) on a network as a microscopic model for active motor protein transport on the cytoskeleton, immersed in the diffusive cytoplasm.
Kern, N., Neri, I., Parmeggiani, A.
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Disrupted functional network integrity and flexibility after stroke: Relation to motor impairments
NeuroImage: Clinical, 2018 Previous studies investigating brain activation present during upper limb movement after stroke have greatly detailed activity alterations in the ipsi- and contralesional primary motor cortices (M1).
Sara Larivière +2 more
doaj +1 more source