Results 121 to 130 of about 305,411 (311)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Selective gating of neuronal activity by intrinsic properties in distinct motor rhythms
, 2015 This research has been supported by the Royal Society, Wellcome Trust (089319), and the Biotechnology and Biological Sciences Research Council (BB/L0011X/1). I thank Drs.
Li, Wen-Chang
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The role of motor proteins in endosomal sorting [PDF]
, 2011 Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie +3 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Neural basis of a visuo-motor transformation in the fly
, 2009 How the outputs of populations of sensory neurons are used by motor systems to generate appropriate behaviour is a long standing question in neuroscience. I address this problem by studying a comparatively simple model system.
core +2 more sources
Age-related deficits in low-level inhibitory motor control [PDF]
, 2011 Inhibitory control functions in old age were investigated with the "masked prime" paradigm in which participants executed speeded manual choice responses to simple visual targets.
Schlaghecken, Friederike +5 more
core +1 more source
, 2023 Increased cortical excitability, associated with brain motor network alterations, has been consistently implicated in the pathology of amyotrophic lateral sclerosis (ALS).
Edmond, Evan Cyril
core +2 more sources
NeuroImage: ClinicalBackground: Strokes frequently result in long-term motor deficits, imposing significant personal and economic burdens. However, our understanding of the underlying neural mechanisms governing motor learning in stroke survivors remains limited - a fact ...
Christiane Dahms +5 more
doaj +1 more source