Results 131 to 140 of about 305,411 (311)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Subcortical electrostimulation to identify network subserving motor control
, 2012 Objectives: Recent anatomical-functional studies have transformed our understanding of cerebral motor control away from a hierarchical structure and toward parallel and interconnected specialized circuits.
Guillaume Herbet +9 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Moving just like you: motor interference depends on similar motility of agent and observer. [PDF]
, 2012 Recent findings in neuroscience suggest an overlap between brain regions involved in the execution of movement and perception of another's movement. This so-called "action-perception coupling" is supposed to serve our ability to automatically infer the ...
Helfer B. +24 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A general magnetic-energy-based torque estimator: validation via a permanent-magnet motor drive [PDF]
, 2008 This paper describes the use of the current–flux-linkage ($i{-}psi$ ) diagram to validate the performance of a general magnetic-energy-based torque estimator.
McGilp, M.I. +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Background/Objectives: Synchronized beta-band oscillations (14–30 Hz) are critical for sensorimotor processing and motor performance. Modulating beta activity either locally in targeted brain regions or globally across sensorimotor networks may ...
Eri Miyauchi +2 more
core +1 more source
Componential coding in the condition monitoring of electrical machines Part 2: application to a conventional machine and a novel machine [PDF]
, 2003 This paper (Part 2) presents the practical application of componential coding, the principles of which were described in the accompanying Part 1 paper.
Gu, Fengshou +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source