Results 81 to 90 of about 1,014,438 (298)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Exploiting SRv6 for Stateless and Per-Connection-Consistent Load Balancing

IEEE Access
This paper proposes a new load-balancing method that supports Per-Connection Consistency (PCC) by leveraging ECMP with standardized routing protocols for operational simplicity.
Ryo Nakamura, Kentaro Ebisawa, Hideaki Hayashi, Tatsuya Fujiwara, Tomoko Okuzawa   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Role of beta-band resting-state functional connectivity as a predictor of motor learning ability

NeuroImage, 2020
It has been suggested that resting-state functional connectivity (rs-FC) between the primary motor area (M1) region of the brain and other brain regions may be a predictor of motor learning, although this suggestion is still controversial.
Hisato Sugata, Kazuhiro Yagi, Shogo Yazawa, Yasunori Nagase, Kazuhito Tsuruta, Takashi Ikeda, Ippei Nojima, Masayuki Hara, Kojiro Matsushita, Kenji Kawakami, Keisuke Kawakami   +10 more
doaj   +1 more source

Global efficiency of the motor network is decreased in Parkinson's disease in comparison with essential tremor and healthy controls

Brain and Behavior, 2021
Background Graph theory (GT) is a mathematical field that analyses complex networks that can be applied to neuroimaging to quantify brain's functional systems in Parkinson's disease (PD) and essential tremor (ET).
Natalia Pelizari Novaes, Joana Bisol Balardin, Fabiana Campos Hirata, Luciano Melo, Edson Amaro Jr., Egberto Reis Barbosa, João Ricardo Sato, Ellison Fernando Cardoso   +7 more
doaj   +1 more source

Electrophysiological Guidance of Epidural Electrode Array Implantation over the Human Lumbosacral Spinal Cord to Enable Motor Function after Chronic Paralysis. [PDF]

, 2019
Epidural electrical stimulation (EES) of the spinal cord has been shown to restore function after spinal cord injury (SCI). Characterization of EES-evoked motor responses has provided a basic understanding of spinal sensorimotor network activity related ...
Beck, Lisa A, Brown, Desmond A, Calvert, Jonathan S, Edgerton, V Reggie, Gerasimenko, Yury P, Gill, Megan L, Grahn, Peter J, Lavrov, Igor A, Lee, Kendall H, Linde, Margaux B, Lopez, Cesar, Sayenko, Dimitry G, Strommen, Jeffrey A, Van Straaten, Meegan G, Veith, Daniel D, Zhao, Kristin D   +15 more
core  

Coupling of Active Motion and Advection Shapes Intracellular Cargo Transport

, 2012
Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion.
H. K. Versteeg, Jochen Guck, Philipp Khuc Trong, Raymond E. Goldstein   +3 more
core   +1 more source

Slowed response to peripheral visual stimuli during strenuous exercise [PDF]

, 2016
Recently, we proposed that strenuous exercise impairs peripheral visual perception because visual responses to peripheral visual stimuli were slowed during strenuous exercise.
Akira Kiyonaga, Hiroaki Tanaka, Masahiro Kokubu, Mizuki Sudo, Soichi Ando, Takaaki Komiyama, Yasuki Higaki   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Using Magnetoencephalography to Advance the Science of Parkinson Disease: A Systematic Review

Brain and Behavior
Purpose Magnetoencephalography (MEG) offers high temporal resolution and whole‐brain spatial coverage, making it a powerful tool to study brain networks.
Saar Kariv, Jeong Woo Choi, Mohsen Benam, Sahil Chilukuri, Amirreza Alijanpourotaghsara, Nader Pouratian   +5 more
doaj   +1 more source