Results 131 to 140 of about 8,574,707 (338)

Disrupted functional network integrity and flexibility after stroke: Relation to motor impairments

open access: yesNeuroImage: Clinical, 2018
Previous studies investigating brain activation present during upper limb movement after stroke have greatly detailed activity alterations in the ipsi- and contralesional primary motor cortices (M1).
Sara Larivière   +2 more
doaj   +1 more source

EEG-based motor network biomarkers for identifying target patients with stroke for upper limb rehabilitation and its construct validity

open access: yesPLoS ONE, 2017
Rehabilitation is the main therapeutic approach for reducing poststroke functional deficits in the affected upper limb; however, significant between-patient variability in rehabilitation efficacy indicates the need to target patients who are likely to ...
Chun-Chuan Chen   +4 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A Self-Organizing Neural Network for Learning a Body-Centered Invariant Representation of 3-D Target Position [PDF]

open access: yes, 1993
This paper describes a self-organizing neural network that rapidly learns a body-centered representation of 3-D target positions. This representation remains invariant under head and eye movements, and is a key component of sensory-motor systems for ...
Bullock, Daniel   +3 more
core   +2 more sources

Transcallosal connectivity of the human cortical motor network

open access: yesBrain Structure and Function, 2016
The organisational and architectural configuration of white matter pathways connecting brain regions has ramifications for all facets of the human condition, including manifestations of incipient neurodegeneration. Although diffusion tensor imaging (DTI)
Kathy L. Ruddy, A. Leemans, R. Carson
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Motor Carrier Service Network Design

open access: yes, 2020
This chapter introduces service network design (SND) operations research models and solution methodologies specifically focused on problems that arise in the planning of operations in the trucking, or motor freight, industry. Consolidation carriers such as less-than-truckload and package trucking companies face flow planning problems to decide how to ...
Bakir, Ilke   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Self-Organizing Neural Network Model for Redundant Sensory-Motor Control, Motor Equivalence, and Tool Use [PDF]

open access: yes, 1992
A neural network is introduced which provides a solution of the classical motor equivalence problem, whereby many different joint configurations of a redundant manipulator can all be used to realize a desired trajectory in 3-D space.
Bullock, Daniel   +2 more
core   +1 more source

Nonlinear Relaxation Dynamics in Elastic Networks and Design Principles of Molecular Machines

open access: yes, 2007
Analyzing nonlinear conformational relaxation dynamics in elastic networks corresponding to two classical motor proteins, we find that they respond by well-defined internal mechanical motions to various initial deformations and that these motions are ...
A. S. Mikhailov   +21 more
core   +2 more sources

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