Results 181 to 190 of about 443,128 (313)

<i>SYNE1</i> Deficiency Manifesting Primarily With Motor Neuron Disease. [PDF]

Neurol Genet
Senghor HVF, Rubio RD, Marco C, Salazar-Villacorta A, Padró-Miquel A, Beltran S, Matalonga L, Márquez F, Sy HA, Sy M, Povedano M, Diop AG, Ndiaye M, Rodríguez Cruz PM.   +13 more
europepmc   +1 more source

Machine‐learning in motor neuron diseases: Prospects and pitfalls

, 2022
Peter Bede, Kai‐Ming Chang, Ee Ling Tan   +2 more
openalex   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Process evaluation and exploration of telehealth in motor neuron disease in a UK specialist centre [PDF]

, 2019
Esther Hobson, Wendy Baird, Mike Bradburn, Cindy Cooper, Sue Mawson, Ann Quinn, Pamela J. Shaw, Theresa Walsh, Christopher McDermott   +8 more
openalex   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Exploring rare coding variants in UK biobank: preliminary associations with motor neuron disease. [PDF]

Front Aging Neurosci
Hu Z, Wan JJ, Yan QQ, Fan Y, Liu J.
europepmc   +1 more source

Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924

Sarah Lépine, Gilles Maussion, Alexandria Schneider, Angela Nauleau-Javaudin, María José Castellanos‐Montiel, Georgina Jiménez Ambriz, Dan Spiegelman, Narges Abdian, Anna Krystina Franco-Flores, Ghazal Haghi, Lale Gursu, Mathilde Chaineau, Thomas M. Durcan   +12 more
openalex   +1 more source

Optimized methods for rapidly dissecting spinal cords and harvesting spinal motor neurons with high survival and purity from rats at different embryonic stages

, 2017
Shudong Chen, Ruimin Tian, Hui Li, Meihui Chen, Hu Zhang, Dingkun Lin   +5 more
openalex   +2 more sources

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

, 2017
Qi‐Jie Zhang, Jin-Jing Li, Xiang Lin, Ying‐Qian Lu, Xinxin Guo, En‐Lin Dong, Miao Zhao, J. He, Ning Wang, Wan‐Jin Chen   +9 more
openalex   +2 more sources