Results 181 to 190 of about 213,623 (266)

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Advancing Human iPSC-Derived Motor Neuron Models Using Glutamatergic Modulators for Synaptic Function Studies

Zuber B, Rostami I, Leuenberger J, Ott G, Khosrozadeh A, Diab R, Saxena S, Nevian T.   +7 more
europepmc   +2 more sources

Boldine as a neuroprotective agent against motor neuron degeneration in models of amyotrophic lateral sclerosis. [PDF]

Front Cell Neurosci
Toro CA, Zhao W, Garcia Silva P, Retamal-Santibáñez D, Rojas F, Pan J, Johnson N, Duarte Y, Cardozo CP, Sáez JC, van Zundert B.   +10 more
europepmc   +1 more source

Golden‐Ratio–Guided Aperiodic Architected Metamaterials with Simultaneously Enhanced Strength and Toughness

Advanced Functional Materials, EarlyView.
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng, Xinxin Wang, Ruochao Zhao, Zhendong Li, Kai Liu, Ke Yuan, Jia An, Xinwei Li, Chee Kai Chua, Zhonggang Wang   +9 more
wiley   +1 more source

An Elongator mouse model of ALS spotlights TDP-43 in the motor neuron nucleolus. [PDF]

Commun Biol
Snow M, Cameron B, Pond R, Trudell R, Snyder S, Torres-Hernandez L, Deschamps D, Tulimaiau D, Hawkinson K, Russell M, Horan D, Walters J, Fox JH, Arlian B, Chariot A, Nguyen L, George L.   +16 more
europepmc   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models. [PDF]

Neurotherapeutics
Lin CY, Lee BC, Zhang PH, Lu SC, Chang WZ, Wang CC, Tsai HJ.   +6 more
europepmc   +1 more source

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

Advanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha, Yingshan Ma, Yong Nam An, Sung‐Un An, Hyeon Hak Jung, Suvi‐Tuuli Varjamo, Jiwon Yoo, Junho Min, Hanvit Kim, Faisal Ahmed, Sang Hoon Chae, Young Min Song, Weiwei Cai, Tawfique Hasan, Zhipei Sun, Dong‐Ho Kang, Hyeon‐Jin Shin, Yunyun Dai, Hoon Hahn Yoon   +18 more
wiley   +1 more source

The Impact of Bulbar and Upper Motor Neuron Involvement on Oculomotor Movement in Amyotrophic Lateral Sclerosis. [PDF]

Brain Behav
Shen D, Liu A, Yang X, Liu Q, Liu M, Cui L.   +5 more
europepmc   +1 more source