Results 211 to 220 of about 443,128 (313)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Shared burden of ultra-rare genetic variants across a spectrum of motor neuron diseases. [PDF]

Transl Neurodegener
Wu G, Chen W, Wuu J, Jain A, Myers J, Cordts I, Rampersaud E, Heckmann JM, Nel M, Granit V, Statland J, Swenson A, Ravits J, McMillan CT, Elman L, Caress J, Burns TM, Pioro EP, Trivedi J, Katz J, Jackson C, Maiser S, Walk D, So Y, McCauley JL, Baker MC, Taylor JP, Zuchner S, Rademakers R, van Blitterswijk M, Benatar M.   +30 more
europepmc   +1 more source

Spirituality and/or religious faith: A means for coping with the effects of amyotrophic lateral sclerosis/motor neuron disease?

, 2015
Mary O’Brien, David Clark
openalex   +2 more sources

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Detour ahead: possible causes of corticospinal tract truncation in upper motor neuron-predominant amyotrophic lateral sclerosis. [PDF]

Brain Commun
Rajagopalan V, Pioro EP.
europepmc   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Imp and Chinmo are required for embryonic motor neuron axon and dendrite targeting. [PDF]

Biol Open
Fisher KH, Lai SL, Doe CQ.
europepmc   +1 more source

Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43 [PDF]

, 2019
Aneesh Donde, Mingkuan Sun, Yun Ha Jeong, Xinrui Wen, Jonathan P. Ling, Sophie Lin, Kerstin E. Braunstein, Shuke Nie, Sheng Wang, Liam Chen, Philip C. Wong   +10 more
openalex   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization. [PDF]

Genes Dev
Lopez DH, Rostam KD, Zamurrad S, Xu S, Mann RS.   +4 more
europepmc   +1 more source