Results 271 to 280 of about 423,991 (315)

Genetic testing for monogenic forms of motor neuron disease/amyotrophic lateral sclerosis in unaffected family members. [PDF]

Eur J Hum Genet
Howard J, Chaouch A, Douglas AGL, MacLeod R, Roggenbuck J, McNeill A.   +5 more
europepmc   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Genotypes and phenotypes of motor neuron disease: an update of the genetic landscape in Scotland. [PDF]

J Neurol
Leighton DJ, Ansari M, Newton J, Cleary E, Stephenson L, Beswick E, Carod Artal J, Davenport R, Duncan C, Gorrie GH, Morrison I, Swingler R, Deary IJ, Porteous M, Chandran S, Pal S, Lothian Birth Cohorts Group, the CARE-MND Consortium.   +17 more
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Adopting a Collaborative Strategy to Address the Complexities of Implanting a Subcutaneous Implantable Cardiac Defibrillator for Secondary Prevention in a Patient With Fabry Disease and Motor Neuron Disease. [PDF]

Cureus
De SK, Luo E, Ahmed A, Shakkottai P, Antony R.   +4 more
europepmc   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Intraventricular Administration of Exosomes from Patients with Amyotrophic Lateral Sclerosis Provokes Motor Neuron Disease in Mice. [PDF]

Acta Naturae
Stavrovskaya AV, Voronkov DN, Pavlova AK, Olshanskiy AS, Belugin BV, Ivanova MV, Zakharova MN, Illarioshkin SN.   +7 more
europepmc   +1 more source

Development and Evaluation of the Telehealth in Motor Neuron Disease System: The TIME Study Protocol.

JMIR Res Protoc
Knox L, Coates E, Griffiths A, Ali Y, Hobson E, McDermott C.   +5 more
europepmc   +1 more source

Correction to: Diagnostic value of neurofilaments in differentiating motor neuron disease from multifocal motor neuropathy. [PDF]

J Neurol
Wohnrade C, Seeliger T, Gingele S, Bjelica B, Skripuletz T, Petri S.   +5 more
europepmc   +1 more source

Small striatal huntingtin inclusions in patients with motor neuron disease with reduced penetrance and intermediate HTT gene expansions. [PDF]

Hum Mol Genet
Roos AK, Stenvall E, Kockum ES, Grönlund KÅ, Alstermark H, Wuolikainen A, Andersen PM, Nordin A, Forsberg KME.   +8 more
europepmc   +1 more source