Results 271 to 280 of about 151,768 (312)
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2014
The loss of afferent and efferent signal transduction following traumatic peripheral nerve injury has immediate and long-term effects on target organs (e.g., muscles and sensory receptors) as well as somatosensory and motor brain areas. The goal of surgical peripheral nerve repair is to mitigate these negative outcomes by restoring the continuity of ...
Wolfgang N. Löscher, Eva L. Feldman
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The loss of afferent and efferent signal transduction following traumatic peripheral nerve injury has immediate and long-term effects on target organs (e.g., muscles and sensory receptors) as well as somatosensory and motor brain areas. The goal of surgical peripheral nerve repair is to mitigate these negative outcomes by restoring the continuity of ...
Wolfgang N. Löscher, Eva L. Feldman
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1999
Motor neuron disease (MND) refers to the group of degenerative disorders characterized by progressive weakness and atrophy of skeletal muscle due to the selective dysfunction and degeneration of upper and/or lower motor neurons. In adults, the most common of these disorders is amyotrophic lateral sclerosis (ALS, i.e., Lou Gehrig’s disease), which ...
Bruce A. Rabin, David R. Borchelt
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Motor neuron disease (MND) refers to the group of degenerative disorders characterized by progressive weakness and atrophy of skeletal muscle due to the selective dysfunction and degeneration of upper and/or lower motor neurons. In adults, the most common of these disorders is amyotrophic lateral sclerosis (ALS, i.e., Lou Gehrig’s disease), which ...
Bruce A. Rabin, David R. Borchelt
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2018
Motor neuron disease (MND) is characterized by progressive muscular weakness due to simultaneous degeneration of lower and upper motor neurons (L/UMNs). Involvement of LMNs, arising from the anterior horns of the spinal cord and brainstem, leads to secondary wasting as a result of muscle denervation.
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Motor neuron disease (MND) is characterized by progressive muscular weakness due to simultaneous degeneration of lower and upper motor neurons (L/UMNs). Involvement of LMNs, arising from the anterior horns of the spinal cord and brainstem, leads to secondary wasting as a result of muscle denervation.
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Independent Nurse, 2008
Aetiology and diagnosis plus support and palliative care options
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Aetiology and diagnosis plus support and palliative care options
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1985
The most severe denervating disorders are those due to degeneration and loss of motor nerve cells. Poliomyelitis is an example of acute anterior horn.cell disease attributable to the cytopathic effects of the virus, but is unlikely to require diagnostic muscle biopsy.
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The most severe denervating disorders are those due to degeneration and loss of motor nerve cells. Poliomyelitis is an example of acute anterior horn.cell disease attributable to the cytopathic effects of the virus, but is unlikely to require diagnostic muscle biopsy.
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2015
In this chapter, the following ten key events in motor neurone disease, also known as amyotrophic lateral sclerosis (ALS), are considered: the first description of ALS by Cruveilhier; discovery of the first SOD1 mutation; use of the ALSFRS (functional rating scale) for determining therapeutic trial outcomes; the contentious issue of establishing the ...
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In this chapter, the following ten key events in motor neurone disease, also known as amyotrophic lateral sclerosis (ALS), are considered: the first description of ALS by Cruveilhier; discovery of the first SOD1 mutation; use of the ALSFRS (functional rating scale) for determining therapeutic trial outcomes; the contentious issue of establishing the ...
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Selective motor activation in organelle transport along axons
Nature Reviews Molecular Cell Biology, 2022Sydney E Cason, Erika L F Holzbaur
exaly
Essays in biochemistry, 1994
Motor neurone disease, or amyotrophic lateral sclerosis, is a serious progressive neurological disorder, characterized by loss of UMN and LMN. Pathological features include characteristic intracytoplasmic MN inclusion bodies and appearances on ubiquitin staining.
A, Goonetilleke +2 more
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Motor neurone disease, or amyotrophic lateral sclerosis, is a serious progressive neurological disorder, characterized by loss of UMN and LMN. Pathological features include characteristic intracytoplasmic MN inclusion bodies and appearances on ubiquitin staining.
A, Goonetilleke +2 more
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Comparative cellular analysis of motor cortex in human, marmoset and mouse
Nature, 2021Trygve E Bakken +2 more
exaly