Results 291 to 300 of about 293,569 (356)

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Determinants and progression of stigma in amyotrophic lateral sclerosis/motor neuron disease. [PDF]

Amyotroph Lateral Scler Frontotemporal Degener
Young CA, Chaouch A, Mcdermott CJ, Al-Chalabi A, Chhetri SK, Bidder C, Edmonds E, Ellis C, Annadale J, Wilde L, Sharrack B, Malaspina A, Leach O, Mills R, Tennant A.   +14 more
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Identification of passive wrist-worn accelerometry outcomes for improved disease monitoring and trial design in motor neuron disease. [PDF]

EBioMedicine
Holdom CJ, Pilkar R, Guo CC, Eijk RPAV, Sethi N, Henderson RD, Ngo ST, Steyn FJ.   +7 more
europepmc   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

Human amyotrophic lateral sclerosis/motor neuron disease: The disease-associated microglial pathway is upregulated while APOE genotype governs risk and survival. [PDF]

Brain Pathol
Ashford BA, Simpson JE, Dawson C, Boche D, Cooper-Knock J, Heath PR, Fillingham D, Appleby-Mallinder C, Wei W, Dunning M, Highley JR.   +10 more
europepmc   +1 more source

Neurologists' understanding of reproductive medicine options for genetic forms of motor neuron disease. [PDF]

Amyotroph Lateral Scler Frontotemporal Degener
Allen S, Howard J, Mcdermott CJ, Boardman F, Mcneill A.   +4 more
europepmc   +1 more source

The Use of Digital Devices to Monitor Physical Behavior in Motor Neuron Disease: Systematic Review.

J Med Internet Res
Musson LS, Mitic N, Leigh-Valero V, Onambele-Pearson G, Knox L, Steyn FJ, Holdom CJ, Dick TJ, van Eijk RP, van Unnik JW, Botman LC, Beswick E, Murray D, Griffiths A, McDermott C, Hobson E, Chaouch A, Hodson-Tole E.   +17 more
europepmc   +1 more source

Clinicopathological correlates in the frontotemporal lobar degeneration-motor neuron disease spectrum. [PDF]

Brain
Carbayo Á, Borrego-Écija S, Turon-Sans J, Cortés-Vicente E, Molina-Porcel L, Gascón-Bayarri J, Rubio MÁ, Povedano M, Gámez J, Sotoca J, Juntas-Morales R, Almendrote M, Marquié M, Sánchez-Valle R, Illán-Gala I, Dols-Icardo O, Rubio-Guerra S, Bernal S, Caballero-Ávila M, Vesperinas A, Gelpi E, Rojas-García R.   +21 more
europepmc   +1 more source