Results 281 to 290 of about 164,738 (314)

Fatigue in motor neuron diseases

Neuromuscular Disorders, 2012
Motor neuron diseases as amyotrophic lateral sclerosis and post-polio syndrome are characterized by prominent muscular weakness and severe motor disability. The prevalence of fatigue in motor neuron diseases is remarkably high, and may contribute significantly to patients' disability and a poor quality of life.
Alon, Abraham, Vivian E, Drory
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Motor neurone disease: an overview

Nursing Standard, 2012
Motor neurone disease (MND) is a relatively rare, progressive and incurable neurological condition affecting patients' speech, mobility and respiratory function. Care of patients with MND is complex and involves various healthcare professionals and services.
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Motor neuron disease in Cantabria

Acta Neurologica Scandinavica, 1988
Sixty-two patients with motor neuron disease (MND), encompassing amyotrophic lateral sclerosis (ALS), progressive bulbar palsy (PBP) and progressive muscular atrophy (PMA), were selected from within a defined area (Cantabria) in northern Spain, from 1974 to 1985. The annual incidence of MND was 1.01 per 100,000 inhabitants and the prevalence rate was 3.
J M, López-Vega, J, Calleja, O, Combarros, J M, Polo, J, Berciano   +4 more
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Motor neuron disease and paraproteinemia

Neurology, 1987
We studied two patients with motor neuron disease and paraproteinemia. One had amyotrophic lateral sclerosis (ALS) and IgG lambda monoclonal gammopathy. The second had slowly progressive muscular atrophy and an IgM kappa paraprotein, followed by a biclonal gammopathy when an IgA kappa paraprotein appeared.
S, Rudnicki, D A, Chad, D A, Drachman, T W, Smith, U E, Anwer, N, Levitan   +5 more
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Epidemiology of Motor-Neuron Diseases

New England Journal of Medicine, 1973
THE motor-neuron diseases as considered here include the clinical syndromes that have been shown to be due to primary abnormalities of anterior-horn cells and motor cranial-nerve nuclei. The term motor-neuron disease is used in a more restricted sense for the syndrome of amyotrophic lateral sclerosis and the clinical components, progressive muscular ...
A R, Bobowick, J A, Brody
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The Electrophysiology of the Motor Neuron Diseases

Neurologic Clinics, 2012
The motor neuron diseases are a set of disorders associated with the selective degeneration of motor neurons. Amyotrophic lateral sclerosis (ALS) is the most common and confers the gravest prognosis. Although ALS occurs with known genetic causes in a small minority, other motor neuron disorders have well-defined genetic mutations.
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Neurofilaments and motor neuron disease

Trends in Cell Biology, 1997
Amyotrophic lateral sclerosis (ALS) is an adult-onset and heterogeneous neurological disorder that affects primarily motor neurons in the brain and spinal cord. Although multiple genetic and environmental factors might be implicated in ALS, the striking similarities in the clinical and pathological features of sporadic ALS and familial ALS suggest that
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Autophagy and Motor Neuron Diseases

2020
Motor neuron diseases (MND) are a group of fatal progressive neurodegenerative diseases, which selectively affect the motor system in the anterior horn of spinal cord, brainstem, cortex and pyramidal tract. Motor neurons could be divided into two groups, which are upper groups in the motor cortex and lower groups in the brain stem and spinal cord. Loss
Xiaojie, Zhang, Kang, Yang, Weidong, Le
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Dementia with motor neuron disease

Neuropathology, 2000
Dementia with motor neuron disease has been described as a new clinicopathologic entity and more than 100 cases have been reported in Japan since 1964. The clinicopathologic criteria in the diagnosis of dementia with motor neuron disease are: (i) frontotemporal lobe‐type dementia with insidious onset, mostly in the presenile period; (ii) neurogenic ...
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Motor Neuron Disease With Parkinsonism

Archives of Neurology, 1996
To report clinical characteristics of patients with combined features of parkinsonism and motor neuron disease (MND).Medical chart review.University medical center.Thirteen patients, identified by computer-assisted search, who had diagnoses of both parkinsonism and MND.Median age was 68 years. There were 7 men and 6 women.
A I, Qureshi, G, Wilmot, B, Dihenia, J A, Schneider, D A, Krendel   +4 more
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