Results 271 to 280 of about 6,008,570 (306)

Flaviviruses in motor neuron disease

Muscle & Nerve, 2005
AbstractSporadic motor neuron disease (MND) causes a progressive loss of motor neurons. West Nile virus can attack motor neurons, so we examined whether flavivirus infection could be detected in MND cases. Spinal cord sections from 22 MND cases were stained immunohistochemically with a flavivirus‐specific antibody.
Roger, Pamphlett, Stephen, Kum-Jew, Nicholas J C, King   +2 more
openaire   +2 more sources

Genetics of motor neuron disease

Current Neurology and Neuroscience Reports, 2006
The number of genes associated with motor neuron degeneration has increased considerably over the past few years. As more gene mutations are identified, the hope arises that certain common themes and/or pathways become clear. In this overview, we focus on recent discoveries related to amyotrophic lateral sclerosis (ALS), spinal muscular atrophies (SMA),
Ludo, Van Den Bosch, Vincent, Timmerman
openaire   +2 more sources

Epidemiology of Motor-Neuron Diseases

New England Journal of Medicine, 1973
THE motor-neuron diseases as considered here include the clinical syndromes that have been shown to be due to primary abnormalities of anterior-horn cells and motor cranial-nerve nuclei. The term motor-neuron disease is used in a more restricted sense for the syndrome of amyotrophic lateral sclerosis and the clinical components, progressive muscular ...
A R, Bobowick, J A, Brody
openaire   +2 more sources

Autophagy and Motor Neuron Diseases

2020
Motor neuron diseases (MND) are a group of fatal progressive neurodegenerative diseases, which selectively affect the motor system in the anterior horn of spinal cord, brainstem, cortex and pyramidal tract. Motor neurons could be divided into two groups, which are upper groups in the motor cortex and lower groups in the brain stem and spinal cord. Loss
Xiaojie, Zhang, Kang, Yang, Weidong, Le
openaire   +2 more sources

The Management of Motor Neurone Disease

1987
Virtually nothing can be found in standard textbooks on the practical management of this fatal condition, with its devastating effect on both patients and their families. Because intellect is unimpaired, the eventual disabilities produce a loss of morale which can be helped only by careful management, both in supportive psychotherapy and in symptomatic
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Conjugal motor neuron disease

Neurology, 1982
We describe a husband and wife with motor neuron disease. The woman had been ill for 10 years with predominantly upper motor neuron signs when her husband developed progressive muscular atrophy. This is the first known report of sporadic motor neuron disease occurring in both partners of a marriage.
D, Chad, H, Mitsumoto, L S, Adelman, W G, Bradley, T L, Munsat, I, Zieper   +5 more
openaire   +2 more sources

Neurofilaments and motor neuron disease

Trends in Cell Biology, 1997
Amyotrophic lateral sclerosis (ALS) is an adult-onset and heterogeneous neurological disorder that affects primarily motor neurons in the brain and spinal cord. Although multiple genetic and environmental factors might be implicated in ALS, the striking similarities in the clinical and pathological features of sporadic ALS and familial ALS suggest that
openaire   +2 more sources

THE PROBLEMS OF MOTOR NEURONE DISEASE

Age and Ageing, 1976
The course of Motor Neurone Disease (MND) is described in 22 patients in respect of the extent and duration of the disabilities. The average stay in hospital in the terminal phase in 20 patients followed to the time of their death was 6.6 months for men and 4.7 months for women.
openaire   +2 more sources

Autophagy in motor neuron diseases

2020
Motor neuron diseases (MNDs) are a wide group of neurodegenerative disorders characterized by the degeneration of a specific neuronal type located in the central nervous system, the motor neuron (MN). There are two main types of MNs, spinal and cortical MNs and depending on the type of MND, one or both types are affected.
openaire   +4 more sources

Motor neurone disease and the life of motor neurones

Medical Journal of Australia, 1997
Amolak S Bansal, Jacqueline A Bansal
openaire   +1 more source