Results 231 to 240 of about 2,514,411 (397)

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

Proceedings of the National Academy of Sciences of the United States of America, 2015
Shuying Sun, Ying Sun, Shuo-Chien Ling, L. Ferraiuolo, Melissa McAlonis-Downes, Yiyang Zou, Kevin Drenner, Yin Wang, D. Ditsworth, Seiya Tokunaga, Alex Kopelevich, B. Kaspar, C. Lagier-Tourenne, D. Cleveland   +13 more
semanticscholar   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

A 3D Atlas of Visceral and Somatic Pelvic Motor Neurons in Whole Mounts of Female and Male Rat Spinal Cords. [PDF]

J Comp Neurol
Fuller-Jackson JP, Yang ZA, Wiedmann NM, Watson A, Jenkins NEC, Keast JR, Osborne PB.   +6 more
europepmc   +1 more source

Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

, 2017
Qi‐Jie Zhang, Jin-Jing Li, Xiang Lin, Ying‐Qian Lu, Xinxin Guo, En‐Lin Dong, Miao Zhao, J. He, Ning Wang, Wan‐Jin Chen   +9 more
openalex   +2 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Single-cell transcriptomic profiling of zebrafish primary motor neurons reveals subtype-specific gene expression signatures. [PDF]

iScience
Nemoz-Billet L, Gil N, Exbrayat-Héritier C, Bouchet M, Malbouyres M, Hughes S, Gillet B, Enriquez J, Bretaud S, Ruggiero F.   +9 more
europepmc   +1 more source

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs

Patricia Bonnavion, Christophe Varin, Gohar Fakhfouri, Pilar Martinez Olondo, Aurélie De Groote, Amandine Cornil, Ramiro Lorenzo, Elisa Pozuelo Fernández, Elsa Isingrini, Quentin Rainer, Kathleen Xu, Eleni T. Tzavara, Érika Vigneault, Sylvie Dumas, Alban de Kerchove d’Exaerde, Bruno Giros   +15 more
openalex   +2 more sources

Small GSK-3 Inhibitor Shows Efficacy in a Motor Neuron Disease Murine Model Modulating Autophagy

, 2016
Estefanía de Munck, Valle Palomo, Emma Muñoz‐Sáez, Daniel I. Pérez, Begoña Gómez-Miguel, M.T. Solas, Carmen Gil, Ana Martı́nez, R.M. Arahuetes   +8 more
openalex   +2 more sources

The proportion of common synaptic input to motor neurons increases with an increase in net excitatory input.

Journal of applied physiology, 2015
A. Castronovo, F. Negro, S. Conforto, D. Farina   +3 more
semanticscholar   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source