Results 61 to 70 of about 3,524,281 (329)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
THE IMPACT OF ACTOR-RELATIONAL DYNAMICS ON INTEGRATED PLANNING PRACTICE [PDF]
, 2021 Integrated planning processes involve an increasing number of actors and aim to create synergy between multiple knowledges in communicative settings. Planning research has acknowledged that the actor-relational aspects of planning processes are not yet ...
Mladenović, Miloš N. +4 more
core +1 more source
Impact of body image on the kinematics of gait initiation
Frontiers in Human NeuroscienceIn daily life, we walk naturally by considering our physical characteristics and formulating appropriate motor plans. However, the impact of changes in body image on walking movements during motor planning remains poorly understood.
Kyosuke Oku +4 more
doaj +1 more source
Transformation of a Virtual Action Plan into a Motor Plan in the Premotor Cortex [PDF]
The Journal of Neuroscience, 2008 Before preparing to initiate a forthcoming motion, we often acquire information about the future action without specifying actual motor parameters. The information for planning an action at this conceptual level can be provided with verbal commands or nonverbal signals even before the associated motor targets are visible.
Yoshihisa, Nakayama +3 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Frontiers in Human Neuroscience, 2019 In the current study, we used functional near-infrared spectroscopy (fNIRS) to compare prefrontal cortex (PFC) activity in adults as they performed two conditions of the Tower of Hanoi (ToH) disk-transfer task that have equivalent executive function (EF)
Kimberly Milla +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
eLifeWhen carrying out a sequence of movements, humans can plan several steps in advance to make the movement smooth.
Raeed H Chowdhury
doaj +1 more source