Results 81 to 90 of about 3,524,281 (329)

Bureau of Motor Vehicles facts and figures

, 2000
Annual; Electronic coverage as of Mar. 1, 2004: 2000-; Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
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NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

History of the Ohio Bureau of Motor Vehicles

, 2001
Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
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Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s disease

Frontiers in Neuroscience
Learning dexterous motor sequences is crucial to autonomy and quality of life but can be altered in Parkinson’s disease (PD). Learning involves optimizing pre-movement planning (preplanning) of multiple sequence elements to reduce computational overhead ...
Kara N. Presbrey, Kara N. Presbrey, Kara N. Presbrey, Thomas A. Wozny, Thomas A. Wozny, Kenneth H. Louie, Kenneth H. Louie, Simon Little, Simon Little, Philip A. Starr, Philip A. Starr, Reza Abbasi-Asl, Reza Abbasi-Asl, Doris D. Wang, Doris D. Wang   +14 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Student needs, aspirations, and accomplishments: essential ingredients in state planning for postsecondary education /mpc, Master Planning Commission.

, 1972
Cover title.; Includes bibliographical references.This report summarizes the findings of the Kansas Master Planning Commission's (mpc) inventory of the educational needs and aspirations of post high school Kansas students. Following introductory material
Kansas. Master Planning Commission.
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The Effects of Reducing Preparation Time on the Execution of Intentionally Curved Trajectories: Optimization and Geometrical Analysis

Frontiers in Human Neuroscience, 2017
When subjects are intentionally preparing a curved trajectory, they are engaged in a time-consuming trajectory planning process that is separate from target selection. To investigate the construction of such a plan, we examined the effect of artificially
Dovrat Kohen, Matan Karklinsky, Yaron Meirovitch, Yaron Meirovitch, Tamar Flash, Lior Shmuelof, Lior Shmuelof, Lior Shmuelof, Lior Shmuelof   +8 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The principles of planning [1973]

, 1973
The Nature of Planning -- Essentials of Planning -- Comprehensive Program of Planning -- Planning Process -- planning ...
Kansas Department of Economic Development, State Planning Division
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How Long Is Too Long: An Individual Time-Window for Motor Planning

Frontiers in Human Neuroscience, 2019
Human motor response time (RT) is determined by the matureness of the preceding neural motor planning process. In the current study, we characterize the temporal boundaries required for the motor planning process, and its impact on the overall motor RT ...
Anat Dahan, Anat Dahan, Rotem Bennet, Miriam Reiner   +3 more
doaj   +1 more source