Results 261 to 270 of about 722,567 (342)

Driving cancer: Motor and adaptor protein dysregulation in endocytic receptor signalling

David H. Kim, Shreya E Boby, Gregory Redpath, Vaishnavi Ananthanarayanan   +3 more
openalex   +1 more source

Segmental isotope labelling and solid-state NMR of a 12 × 59 kDa motor protein: identification of structural variability

, 2018
Thomas Wiegand, Riccardo Cadalbert, Christine von Schroetter, Frédéric H.‐T. Allain, Beat H. Meier   +4 more
openalex   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes. [PDF]

Kidney Int, 2019
Arif E, Solanki AK, Srivastava P, Rahman B, Tash BR, Holzman LB, Janech MG, Martin R, Knölker HJ, Fitzgibbon WR, Deng P, Budisavljevic MN, Syn WK, Wang C, Lipschutz JH, Kwon SH, Nihalani D.   +16 more
europepmc   +1 more source

3P152 Library antibodies inhibiting Mycoplasma mobile gliding suggest topology and movements of gliding proteins(Molecular motor,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Chie Kawaguchi, Shuhei Yoshi, Makoto Miyata   +2 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Senataxin, the yeast Sen1p orthologue: Characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease

, 2006
Ying-Zhang Chen, Sayed Hossein Hashemi, Susan K. Anderson, Yongzhao Huang, Maria-Ceu Moreira, David R. Lynch, Ian A. Glass, Phillip F. Chance, Craig L. Bennett   +8 more
openalex   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Motor Protein Accumulation on Antiparallel Microtubule Overlaps. [PDF]

Biophys J, 2016
Kuan HS, Betterton MD.
europepmc   +1 more source