Results 211 to 220 of about 283,436 (252)
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Motor proteins transporting cargos
The European Physical Journal E, 2005Processive motor proteins such as kinesin and myosin-V are enzymes that use the energy of ATP hydrolysis to travel along polar cytoskeletal filaments. One of the functions of these proteins is the transport of vesicles and protein complexes that are linked to the light chains of the motors. Modeling the light chain by a linear elastic spring, and using
Zeldovich, K. B. +2 more
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Mutational Analysis of Motor Proteins
Annual Review of Physiology, 1996Mutations in motor proteins, which can arise by design or randomly, provide powerful insights into the normal function of the protein. This review organizes the available data on mutations of members of the myosin, kinesin, and dynein superfamilies of motor proteins.
H L, Sweeney, E L, Holzbaur
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The Bacterial RecA Protein as a Motor Protein
Annual Review of Microbiology, 2003▪ Abstract  The bacterial RecA protein plays a central role in the repair of stalled replication forks, double-strand break repair, general recombination, induction of the SOS response, and SOS mutagenesis. The major activity of RecA in DNA metabolism is the promotion of DNA strand exchange reactions.
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The Mitochondrial Protein Import Motor
Biological Chemistry, 2000Mitochondrial proteins are synthesized as precursor proteins in the cytosol and are posttranslationally imported into the organelle. A complex system of translocation machineries recognizes and transports the precursor polypeptide across the mitochondrial membranes.
Strub, Andreas +3 more
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Motor proteins in cell division
Trends in Cell Biology, 1991The movements of eukaryotic cell division depend upon the conversion of chemical energy into mechanical work, which in turn involves the actions of motor proteins, molecular transducers that generate force and motion relative cytoskeletal elements. In animal cells, microtubule-based motor proteins of the mitotic apparatus are involved in segregating ...
K E, Sawin, J M, Scholey
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Motor proteins for cytoplasmic microtubules
Current Opinion in Cell Biology, 1992It has been thought that motile structures within the cell are driven toward the plus and minus ends of microtubules by the ATPases, kinesin and dynein, respectively. Recently obtained data indicate that this model is far too simplistic. Kinesin is now understood to be one representative of a family of proteins. Another member of the kinesin family has
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Association of motor proteins with membranes
Current Opinion in Cell Biology, 1991The motility of intracellular components, and of the cell as a whole, is mediated by cytoplasmic motor proteins. This review discusses what is known about the binding of cytoplasmic motors to membranes. Mechanisms by which these interactions may result in observed motile phenomena are proposed.
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Mechanisms of motor protein reversal
Current Opinion in Cell Biology, 2001Members of the kinesin superfamily of microtubule-based motors and the myosin superfamily of actin-based motors that move 'backwards' have been identified. As the core catalytic domains of myosins and kinesins are similar in structure, this raises the intriguing questions of how direction reversal is accomplished and whether kinesins and myosins share ...
T, Hasson, R E, Cheney
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Protein profile, 1996
Progress regarding the kinesins is now being made at a rapid and accelerating rate. The in vivo-functions, and biophysical and enzymatic properties of kinesin itself are being explored at ever increasing levels of detail. The kinesin-related proteins now number several dozen, and although more is known about primary structure than function for most of ...
G S, Bloom, S A, Endow
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Progress regarding the kinesins is now being made at a rapid and accelerating rate. The in vivo-functions, and biophysical and enzymatic properties of kinesin itself are being explored at ever increasing levels of detail. The kinesin-related proteins now number several dozen, and although more is known about primary structure than function for most of ...
G S, Bloom, S A, Endow
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Microtubule-based motor proteins
Current Opinion in Cell Biology, 1990Virtually all eukaryotes actively transport or position intracellular components (for example, chromosomes or membrane-bounded organelles), and some cells have developed means of moving through aqueous environments or on top of substrates. Such motile processes invob,'ed interactions between cytoskeletal fibers and 'motor' proteins that generate force ...
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