Results 91 to 100 of about 148,167 (311)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Assessment Protocol of Motor Programming Skills after Cerebrovascular Insults [PDF]

open access: bronze, 2022
Dalia M. Othman   +3 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Supporting Young Children’s Physical Development through Tailored Motor Competency Interventions within a School Setting

open access: yesChildren
Background/Objectives: This study investigated how tailored motor competency (MC) interventions within a bespoke Scheme of Work (SOW) can support young children’s physical development (PD) by enhancing fine motor skills (FMS) and gross motor skills (GMS).
Ellie Huggett, Kristy Howells
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The impact of 8 weeks of Heidelberg Ballschule games on the motor proficiency and visual-motor skills of 7-9 year-old female students

open access: yesInternational Journal of Adolescence and Youth
The study investigated the effects of Heidelberg Ballschule motor proficiency and visual-motor skills of 7–9 year-old girls. A sample of 30 girls participated in a semi-experimental study, with pre-test and post-test evaluations conducted.
Samira Jafari   +2 more
doaj   +1 more source

The Effect of Perceptual – Motor Experience on Motor Development Quotient of Fine and Gross Motor Skills in 5-8-Month-Old Infants [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2010
The purpose of this study was to investigate the effect of perceptual – motor experience on motor development quotient of fine and gross motor skills in infants.
Alireza Farsi   +3 more
doaj  

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