Results 51 to 60 of about 4,187,793 (246)
Impairment in movement skills of children with autism spectrum disorders [PDF]
, 2009 We undertook this study to explore the degree of impairment in movement skills in children with autistic spectrum disorders (ASD) and a wide IQ range.
Charman, Tony; id_orcid +24 more
core +1 more source
Oral motor and language development. [PDF]
, 2002 Manual gesture has been shown to be related to normal language development, in that early gesture users become early talkers. In addition, different groups of speech and language impaired individuals (left-hemisphere CVA patients with nonfluent dysphasia,
Alcock, K. J., Gordon, E.
core +4 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Mood changes after maximal exercise testing in subjects with symptoms of exercise dependence
, 2004 Considering exercise has positive and negative reinforcing properties, the mood states of sedentary, nonexercise-dependent and exercise-dependent volunteers were compared after maximal exercise testing.
Marco Túlio de Mello +11 more
core +1 more source
The relationship between motor proficiency, bilateral vestibular hypofunction and dynamic visual acuity in children with congenital or early acquired sensorineural hearing loss [PDF]
, 2010 Includes bibliographical references (leaves 105-115).The functional integrity of the vestibular system in children is not often tested. Due to the close relationship between the cochlea and the peripheral vestibular system, the function of the vestibular
Geldenhuys, Wilhelmien
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2013 Visual-motor skill is fundamental to human development and is an important component of psychological evaluations. the goal of the present study was to determine whether there is a correlation between visual-motor development, as measured by the Bender ...
Schoen, Teresa Helena [UNIFESP] +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Społeczeństwo, Edukacja, JęzykThe article addresses the issue of difficulties in the motor domain and the support of motor development in preschool and early school-age children.
Renata Biernat
doaj +1 more source