Results 71 to 80 of about 4,187,793 (246)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Effects of Transcranial Direct Current Stimulation and Selective Motor Training on Fine Motor Skills in Children with Autism Spectrum Disorders

مجله پژوهش در علوم توانبخشی, 2017
Introduction: Transcranial direct current stimulation (tDCS) is a noninvasive technique that modulates motor performance and learning. Previous studies have shown that tDCS over the primary motor cortex (M1) can facilitate consolidation of various motor ...
Elham Mahmoodifar, Ahmadreza Movahedi, Elaheh Arab-Ameri, Salar Faramarzi   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Determine motor status of children with motor skills disorders using two scales of Bleck and Capute

Journal of Holistic Nursing and Midwifery, 2014
Introduction: The motor prognosis of children with motor skills disorders is a major issue for their parents and the health professionals involved in their management. Prediction of prognosis in infancy is very difficult. Available and simple tests which
Parvin Raji, Norodin Nokhostin Ansari, Shohre Jalaie, Mahmood Mahmoudian   +3 more
doaj  

تأثیر یک دوره آموزش بدمینتون بر جبران فعالیت‌های بنیادی در کودکان مبتلا به عقب‌ ماندگی حرکتی

مجله پژوهش در علوم توانبخشی, 2018
مقدمه: مهارت‌های حرکتی در کودکان با گذراندن مراحل رشد و نمو به بیشترین میزان ممکن برای پیشرفت در هر فرد نزدیک می‌گردد. با این وجود، رسیدن به این هدف به صورت خودکار حاصل نمی‌شود.
Farnoosh Fotrousi, Mahmoud Sheikh, Rasoul Hemayattalab, Davood Homanian   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Individual differences in basic numerical skills: The role of executive functions and motor skills [PDF]

, 2019
The aim of the current study was to explore individual differences in basic numerical skills in a normative sample of 151 kindergarteners (mean age = 6.45 years).
Fred W Mast (18252274), Claudia M Roebers (18252277), Gashaj, Venera, Oberer, Nicole, Venera Gashaj (14147157), Roebers, Claudia, Mast, Fred W., Nicole Oberer (18252301)   +7 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The effectiveness of fine motor correction techniques in children aged 8–9 years with severe speech disorders

Вестник Тамбовского университета. Серия: Гуманитарные науки
Importance. Based on the psychological and pedagogical characteristics and developmental characteristics of children with severe speech disorders, we improved and tested during a longitudinal study a technique for the correction of fine motor skills ...
A. E. Dedya, V. V. Gridneva, A. V. Poteshkin   +2 more
doaj   +1 more source