Results 81 to 90 of about 4,187,793 (246)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Gymnastics as an intervention for enhancing children's motor development: A systematic literature review [PDF]

open access: yesBIO Web of Conferences
The optimal development of motor skills in childhood is crucial for ensuring good health and independence and engaging in an active lifestyle. The use of gymnastics as a structured and universal practice may contribute to the improvement of balance ...
Wijayanti Karunia   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Dance as a strategy to strengthen motor skills in relation to the laterality and coordination in second grade students [PDF]

open access: yes, 2023
Las habilidades motoras son fundamentales en la vida del niño, puesto que influyen en su desarrollo físico, cognitivo y emocional. Es entonces vital desarrollar dichas habilidades desde los primeros años de infancia, con ayuda de movimientos físicos ...
Garcés A, Genis Ximena   +1 more
core  

Lifestyle in children with and without developmental coordination disorder

open access: yesFisioterapia e Pesquisa, 2014
This study aimed to characterize the lifestyle of schoolchildren aged 11 to 13 years with and without developmental coordination disorder (DCD). The study included 108 schoolchildren enrolled in a public school in Florianópolis (SC). For motor evaluation
Andressa Ribeiro Contreira   +3 more
doaj   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Bureau of Motor Vehicles facts and figures

open access: yes, 2000
Annual; Electronic coverage as of Mar. 1, 2004: 2000-; Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
core  

Effect of a governmentally-led physical activity program on motor skills in young children attending child care centers: a cluster randomized controlled trial [PDF]

open access: yes, 2013
OBJECTIVE: To assess the effect of a governmentally-led center based child care physical activity program (Youp'la Bouge) on child motor skills.Patients and methods: We conducted a single blinded cluster randomized controlled trial in 58 Swiss child care
Jérôme Barral   +25 more
core   +1 more source

Kinetics and Kinematics of Shape Tracing in Children with Probable Developmental Coordination Disorder (pDCD)

open access: yesChildren
Background: Children with developmental coordination disorder (DCD) exhibit visual–motor deficits affecting handwriting. Shape tracing, a key prerequisite for handwriting, supports motor and cognitive development but remains underexplored in research ...
Michal Hochhauser   +3 more
doaj   +1 more source

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