ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Protocol for evaluating the effects of tDCS and tACS on brain oscillations and motor symptoms in patients with Parkinson's disease. [PDF]
Liu J, Bu J.
europepmc +1 more source
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Non-motor symptoms as critical predictors of quality of life in Parkinson's disease: a machine learning approach. [PDF]
Magano D +4 more
europepmc +1 more source
Motor and non-motor symptoms in cervical dystonia
In this thesis, we detected a high frequency of non motor symptoms (NMS) in patients with cervical dystonia (CD) , with a high impact on quality of life (HR-QoL). Psychiatric co-morbidity and fatigue are most likely primary symptoms and part of the phenotype of CD, while excessive daytime sleepiness and impaired sleep quality were highly related to ...
openaire +1 more source
Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan +3 more
wiley +1 more source
The effects of aquaporin-4 polymorphisms on glymphatic function and motor symptoms in Parkinson's disease. [PDF]
Qin J +17 more
europepmc +1 more source
Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt +8 more
wiley +1 more source
The non-motor symptoms questionnaire and non-motor symptoms scale for use in Sweden
Objective: To translate the Non-Motor Symptoms Questionnaire (NMSQ) and the Non-Motor Symptoms Scale (NMSS) into Swedish, and test their linguistic validity and user-friendliness. Background: Non-motor symptoms (NMS) are common but under recognized among people with Parkinson’sdisease (PwPD).
Hagell, Peter +3 more
openaire +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source

