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Motor symptoms of Parkinson's disease: critical markers for early AI-assisted diagnosis. [PDF]

open access: yesFront Aging Neurosci
Yang N   +6 more
europepmc   +1 more source

Motor and non-motor symptoms in blepharospasm: clinical and pathophysiological implications

Journal of Neurology, 2019
Patients with blepharospasm in addition to involuntary contraction of the orbicularis oculi muscle also have non-motor symptoms (psychiatric, sleep, cognitive, and ocular). In this paper, we investigated the relationship of non-motor with motor symptoms and the total burden of non-motor symptoms in patients with blepharospasm.
Giovanni Defazio   +2 more
exaly   +5 more sources

Neuroplasticity in dystonia: Motor symptoms and beyond

2022
This chapter first focuses on the role of altered neuroplasticity mechanisms and their regulation in the genesis of motor symptoms in the various forms of dystonia. In particular, a review of the available literature about focal dystonia suggests that use-dependent plasticity may become detrimental and produce dystonia when practice and repetition are ...
Angelo, Quartarone   +1 more
openaire   +2 more sources

Motor symptoms in Parkinson's disease

2007
Publisher Summary This chapter reviews the pathophysiological mechanisms and the clinical features of motor manifestations of Parkinson's disease (PD). The most typical and easily recognized symptom of PD is unilateral, 4–6 Hz, rest tremor. This is differentiated from the typical 5–8 Hz postural tremor of essential tremor (ET), enhanced physiologic ...
Joohi, Shahed, Joseph, Jankovic
openaire   +2 more sources

Management of Motor and Non-Motor Symptoms in Parkinson’s Disease

CNS Drugs, 2013
Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects approximately 1 % of people over the age of 60 years. Accurate diagnosis and individualized assessment of the risks and benefits of available antiparkinsonian medications as well as specific clinical features and the phase of disease should guide treatment for ...
Fabienne, Sprenger, Werner, Poewe
openaire   +2 more sources

Fatigue in Parkinson's disease: Motor or non-motor symptom?

Parkinsonism & Related Disorders, 2013
Fatigue is one of the most disabling symptoms in patients with Parkinson's disease (PD), with a significant impact on patients' quality of life. Clinical studies using ad hoc questionnaires showed that in PD fatigue is associated with non-motor as well motor symptoms.
FABBRINI, Giovanni   +5 more
openaire   +3 more sources

Treatment of the Motor and Non-Motor Symptoms in Parkinson's Disease According to Cluster Symptoms Presentation

Current Drug Targets, 2014
The term Parkinson’s disease has been changed in ‘Parkinson's diseases’ to describe different clinical entities observed in several studies investigating the existence of PD subtypes. PD patients could be grouped based on clinical features. By considering only motor symptoms, we can classically distinguish two groups: “ the tremorigen-form” and ...
LAURETANI, Fulvio   +6 more
openaire   +3 more sources

Quantification of the motor symptoms of Parkinson's disease

2017 8th International IEEE/EMBS Conference on Neural Engineering (NER), 2017
Parkinson's disease (PD) is a neurodegenerative disorder and severely affects patients' daily lives. The diagnosis depends on the presence of one or more common motor symptoms of the disease. As PD is chronic and slowly progressive, the symptoms continue and worsen over a long period of time.
Qifan Bai   +7 more
openaire   +1 more source

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