Results 1 to 10 of about 1,436,982 (204)

Nonmotor Symptoms in Patients with PARK2 Mutations [PDF]

open access: yesParkinson's Disease, 2011
Decreased 123I-meta-iodobenzylguanidine (MIBG) uptake in MIBG myocardial scintigraphy, olfactory dysfunction, and rapid eye movement (REM) sleep behavior disorder (RBD) are considered useful early indicators of Parkinson disease.
Asako Yoritaka   +5 more
doaj   +3 more sources

Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease [PDF]

open access: yesParkinson's Disease, 2011
Nonmotor symptoms of Parkinson's disease (PD) may emerge secondary to the underlying pathogenesis of the disease, while others are recognized side effects of treatment.
Ariane Park, Mark Stacy
doaj   +3 more sources

Temporal patterns of motor and nonmotor symptom emergence in Parkinson’s disease: a cluster analysis

open access: yesClinical Parkinsonism & Related Disorders
Background: Parkinson’s disease is a heterogeneous disorder characterized by a broad spectrum of motor and nonmotor symptoms. Recent studies suggest that the order of motor and nonmotor symptom development may indicate different subtypes of Parkinson’s ...
Yoko Sugimura   +6 more
doaj   +1 more source

Therapeutic Effect of Levodopa/Carbidopa/Entacapone on Sleep Disturbance in Patients with Parkinson’s Disease [PDF]

open access: yesJournal of Movement Disorders, 2020
Objective To investigate the efficacy of levodopa/carbidopa/entacapone (LCE) at bedtime for treating sleep disturbance in patients with Parkinson’s disease (PD) with motor fluctuations.
Kye Won Park   +6 more
doaj   +1 more source

Correlates of polyneuropathy in Parkinson’s disease

open access: yesAnnals of Clinical and Translational Neurology, 2020
Objective Previous studies in Parkinson’s disease (PD) patients have demonstrated a high prevalence of polyneuropathy (PNP) and pronounced alpha‐Synuclein pathology in dermal nerve fibers already at early disease stages.
Eva Kühn   +11 more
doaj   +1 more source

Parkinson’s Disease Case Ascertainment in the Sister Study: A Cohort for Environmental Health Research

open access: yesJournal of Parkinson’s Disease, 2023
Background: Large prospective studies are essential for investigating the environmental causes of Parkinson’s disease (PD), but PD diagnosis via clinical exams is often infeasible in such studies.
Zichun Cao   +10 more
doaj   +1 more source

Nonmotor symptoms in LRRK2 G2019S associated Parkinson's disease. [PDF]

open access: yesPLoS ONE, 2014
Idiopathic Parkinson's disease (IPD) and LRRK2-associated PD (LRRK2-PD) might be expected to differ clinically since the neuropathological substrate of LRRK2-PD is heterogeneous.
Carles Gaig   +12 more
doaj   +1 more source

NON-MOTOR SYMPTOMS OF PARKINSON DISEASE

open access: yesПаёми Сино, 2021
Objective: To assess the specific non-motor symptoms of Parkinson disease (PD) at its early (preclinical) stages using the NMSQuest scale. Methods: The respondents were divided into 2 groups.
N.A. ZARIPOV   +3 more
doaj   +1 more source

High Prevalence of Gastroesophageal Reflux Disease in Parkinson’s Disease: A Questionnaire-Based Study

open access: yesParkinson's Disease, 2013
The aim of this study is to investigate the frequency and clinical features of gastroesophageal reflex disease (GERD) in Parkinson’s disease (PD).
Tetsuya Maeda   +4 more
doaj   +1 more source

Changes in Gut Microbiome Following Acupuncture and Moxibustion in Patients With Parkinson Disease: Protocol for a Single-Group, Prospective, Observational Study

open access: yesJMIR Research Protocols
BackgroundParkinson disease (PD), a prevalent neurodegenerative disorder characterized by motor and nonmotor symptoms, is becoming increasingly prevalent worldwide.
Han-Gyul Lee   +4 more
doaj   +1 more source

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