Results 41 to 50 of about 1,436,982 (204)

Clinical Features of Parkinson’s Disease: The Evolution of Critical Symptoms

open access: yesBiology, 2020
Parkinson’s disease (PD) is a multi-attribute neurodegenerative disorder combining motor and nonmotor symptoms without well-defined diagnostic clinical markers.
Csaba Váradi
doaj   +1 more source

Identifying the clusters within nonmotor manifestations in early Parkinson's disease by using unsupervised cluster analysis. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Classical and data-driven classifications of Parkinson's disease (PD) are based primarily on motor symptoms, with little attention being paid to the clustering of nonmotor manifestations.
Hui-Jun Yang   +4 more
doaj   +1 more source

Nonmotor Symptoms in Parkinson's Disease [PDF]

open access: yesInternational Journal of Neuroscience, 2011
The recognition and treatment of nonmotor symptoms are increasingly emphasized in the care of Parkinson's disease (PD) patients. This manuscript will review signs and symptoms localized, generally, to the cortex, basal ganglia, brainstem, spinal cord, and peripheral nervous system.
openaire   +2 more sources

Distribution and correlation of psychiatric symptoms in early stages of Parkinson’s disease [PDF]

open access: yesRomanian Journal of Neurology, 2018
The premotor phase of Parkinson Disease (PD) precedes the classical motor phase, and the clinical picture is dominated by nonmotor symptoms. The psychiatric symptoms, an important category of nonmotor symptoms, need to be evaluated and treated. The study
Nicoleta Tohanean   +2 more
doaj   +1 more source

Multimodal biofeedback for Parkinson’s disease motor and nonmotor symptoms

open access: yesBrain Science Advances, 2023
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor retardation, myotonia, quiescent tremor, and postural gait abnormality, as well as nonmotor symptoms such as anxiety and depression.
Zhongyan Shi   +9 more
doaj   +1 more source

Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different methods of mapping DBS effects to determine sweetspots. While having a direct impact on surgical targeting and postoperative programming in DBS, these methods ...
Till A. Dembek   +7 more
wiley   +1 more source

Study of Nonmotor Manifestations in a Sample of Egyptian Multiple Sclerosis Patients [PDF]

open access: yesAl-Azhar International Medical Journal, 2000
Background: Nonmotor symptoms are commonly reported with multiple sclerosis (MS) patients including fatigue, depression, anxiety, pain, cognitive impairment, sleep disorders, pseudobulbar affect, sexual dysfunction, paroxysmal symptoms, and bladder and
doaj   +1 more source

Nonmotor symptom burden grading as predictor of cognitive impairment in Parkinson’s disease

open access: yesBrain and Behavior, 2021
Background Identifying predictors of incident cognitive impairment (CI), one of the most problematic long‐term outcomes, in Parkinson's disease (PD) is highly relevant for personalized medicine and prognostic counseling. The Nonmotor Symptoms Scale (NMSS)
Panteleimon Oikonomou   +15 more
doaj   +1 more source

FOCAL DYSTONIAS: NON-MOTOR SYMPTOMS AND COMORBIDITIES

open access: yesМедицинский совет, 2017
Dystonia is a common extrapyramidal disease. It is characterized by both motor and non-motor manifestations, which include pain, sensory disorders and excessive physical activity.
V. A. Tolmachyova
doaj   +1 more source

Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?

open access: yes, 2011
Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before.Methods:

core   +1 more source

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