Results 61 to 70 of about 1,436,982 (204)
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin +5 more
wiley +1 more source
The GBA1 p.E427K (p.E388K) Variant Is a Risk Factor for Synucleinopathies: A Meta‐Analysis
Movement Disorders, EarlyView.Abstract Background Variants in GBA1 are important genetic risk factors for synucleinopathies, including Parkinson's disease (PD). Although several GBA1 variants are established risk or severity modifiers, the role of the p.E427K variant remains unclear.
Leah V. Chifamba +30 more
wiley +1 more source
Nonmotor Symptoms in Parkinson’s Disease in 2012: Relevant Clinical Aspects [PDF]
, 2012 Nonmotor symptoms (NMSs) of Parkinson’s disease (PD) are common, but they are often underrecognized in clinical practice, because of the lack of spontaneous complaints by the patients, and partly because of the absence of systematic questioning by the ...
Marie Vidailhet +4 more
core +1 more source
, 2023 Supplemental Material, sj-pdf-1-bsa-10.26599_BSA.2023.9050015 for Multimodal biofeedback for Parkinson’s disease motor and nonmotor symptoms by Zhongyan Shi, Lei Ding, Xingyu Han, Bo Jiang, Jiangtao Zhang, Dingjie Suo, Jinglong Wu, Guangying Pei, Boyan ...
Bo Jiang (76119) +9 more
core +1 more source
Nonmotor Symptoms of Parkinson’s Disease as Predictors of Dementia [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2017 AbstractSome nonmotor symptoms (NMS) of Parkinson’s disease (PD) have been shown to increase the risk of developing dementia. A total of 52 PD patients without dementia at baseline were examined for NMS over 36 months. Mini-Mental State Examination, Dementia Rating Scale–2, and caregiver-derived (Clinical Dementia Rating) scores were employed to rate ...
Mohammed Wasif, Hussain +1 more
openaire +2 more sources
Parkinson's Disease, 2018 Dietary habits may differ between Parkinson’s disease (PD) patients of different ethnicities. The primary aim of this cross-sectional analysis was to compare dietary habits in a multiethnic PD population and investigate potential nonmotor differences ...
Anna Sauerbier +7 more
doaj +1 more source
Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study
Movement Disorders, EarlyView.Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri +13 more
wiley +1 more source
Brain and Behavior, 2023 Background Gastrointestinal symptoms are common in Parkinson's disease (PD), but their neurophysiological correlates are not well understood. We recently reported that functional gastrointestinal symptoms were not associated with asymmetry per se but ...
Kirsi Murtomäki +12 more
doaj +1 more source
Movement Disorders, EarlyView.Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer +27 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota +14 more
wiley +1 more source