Results 51 to 60 of about 1,436,982 (204)

Nonmotor Symptoms in Amyotrophic Lateral Sclerosis: A Systematic Review

, 2017
Background: ALS is a progressive neurodegenerative disease with no curative treatment. Nonmotor symptoms presenting in ALS may cause significant distress, worsen prognosis, and affect survival.
Felix Jozsa, Ammar Al-Chalabi, Al-Chalabi, Ammar, Ton Fang, Fang, Ton, Jozsa, Felix   +5 more
core   +1 more source

Video‐based diagnostics supported by artificial intelligence as an opportunity to address the epilepsy diagnostic gap: A narrative review

Epilepsia, EarlyView.
Abstract Despite advancements in epilepsy care, a substantial diagnostic gap persists, particularly in resource‐limited settings. This narrative review explores the potential of video‐based diagnostics augmented by artificial intelligence (AI) to address this gap by enabling earlier and more accessible seizure detection and classification.
Gadi Miron, Robert Terziev, Maximilian Schöls, John McLaren, Tobias Loddenkemper, Jörg Wellmer, Sigrid Mues, Christian Meisel   +7 more
wiley   +1 more source

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou, Yen‐Cheng Shih, Yi‐Hsiu Chen, Po‐Tso Lin, Chun‐Fu Lin, Po‐Chun Chu, Hao‐Li Liu, Cheng‐Chia Lee, Hsiang‐Yu Yu   +8 more
wiley   +1 more source

Nonmotor symptoms in Parkinson’s disease: the dark side of the moon

, 2010
Nonmotor symptoms may appear during the course of Parkinson’s disease, complicating the advanced phase in particular, but are also common in the premotor phase of Parkinson’s disease.
Ubaldo Bonuccelli, Roberto Ceravolo, Lorenzo Kiferle, Carlo Rossi   +3 more
core   +1 more source

Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy

Epilepsia, EarlyView.
Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren, Cuiping Xu, Na Clara Pan, Runshi Gao, Wei Shu, Xueyuan Wang, Xi Zhang, Li Wang, Liping Zhang, Xiaoming Yan, Xiaohua Zhang, Tao Yu, Mohamad Z Koubeissi, Yuping Wang   +13 more
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean, Lena C. O’Flynn, Michelle Ciucci, Cynthia Fox, Jessica E. Huber, Supraja Anand, Maira Rozenfeld Olchik, Jibrin S. Usman, Adam P. Vogel, Bettina Aguiar, Diana Khasanova, Dharshini Manoharan, Lorraine Ramig, Angela Roberts, Federico Rodriguez‐Porcel, Kristina Simonyan, Julie M. Barkmeier‐Kraemer   +16 more
wiley   +1 more source

Longitudinal Associations between Depression, Daytime Sleepiness, and Caregiver Strain in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Objective Examine the longitudinal relationship between caregiver strain and Parkinson's patient depression, daytime sleepiness, and treatment with dopamine agonists and antidepressants. Background Parkinson's disease (PD) is a neurodegenerative disorder, in which family caregivers play an integral role in patient care.
Sarah Holden, Sean P. Lane, Madison Christopher, Lisa Mann, Julie H. Carter, Joseph Quinn, Jiayun Xu   +6 more
wiley   +1 more source

Unravelling the nonmotor mysteries of Parkinson disease

, 2016
Parkinson disease (PD) is now regarded as a mixed motor, nonmotor and multiorgan disorder rather than a pure movement disorder. Nonmotor symptoms (NMS) have underpinned this conceptual change, and new criteria for clinical and prodromal diagnosis of PD ...
K. Ray Chaudhuri, Sauerbier, Anna; id_orcid, Anna Sauerbier, Chaudhuri, K. Ray   +3 more
core   +1 more source

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis, Omer Anis, Abhishek Lenka, Junaid H. Siddiqui   +3 more
wiley   +1 more source

New Symptomatic Treatments for the Management of Motor and Nonmotor Symptoms of Parkinson's Disease

, 2017
Motor symptoms are core features of Parkinson's disease, while nonmotor symptoms are present from the prodromal stage. Management strategies for the motor symptoms of Parkinson's disease have been widely researched and there have been many advances ...
Peter Jenner, Raquel N. Taddei, Jenner, Peter, Spinnato, Federica, Taddei, Raquel N., Federica Spinnato   +5 more
core   +1 more source