Results 51 to 60 of about 7,252 (163)

Dietary Variations in a Multiethnic Parkinson’s Disease Cohort and Possible Influences on Nonmotor Aspects: A Cross-Sectional Multicentre Study

Parkinson's Disease, 2018
Dietary habits may differ between Parkinson’s disease (PD) patients of different ethnicities. The primary aim of this cross-sectional analysis was to compare dietary habits in a multiethnic PD population and investigate potential nonmotor differences ...
Anna Sauerbier, Anette Schrag, Pablo Martinez-Martin, Lynsey J. Hall, Miriam Parry, Laurie K. Mischley, Panagiotis Zis, K. Ray Chaudhuri   +7 more
doaj   +1 more source

Deep Brain Stimulation of the Posterior Subthalamic Area and the Subthalamic Nucleus in Tremor‐Dominant Parkinson's Disease: A Randomized, Crossover Trial

Movement Disorders, EarlyView.
Abstract Background The posterior subthalamic area (PSA) is a familiarized target for Parkinson's disease (PD) in the lesioning era and has recently been reconsidered for deep brain stimulation (DBS). Objective The aim of this study was to compare the therapeutic efficacy of PSA versus subthalamic nucleus (STN) DBS in tremor‐dominant Parkinson's ...
Zhengyu Lin, Zhitong Zeng, Yixin Pan, Peng Huang, Yuyan Tan, Chencheng Zhang, Bomin Sun, Dianyou Li   +7 more
wiley   +1 more source

The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project

Parkinson's Disease, 2011
Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson’s disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated.
Vinod Metta, Kartik Logishetty, P. Martinez-Martin, Heather M. Gage, P. E. S. Schartau, T. K. Kaluarachchi, Anne Martin, Per Odin, P. Barone, Fabrizio Stocchi, A. Antonini, K. Ray Chaudhuri   +11 more
doaj   +1 more source

The GBA1 p.E427K (p.E388K) Variant Is a Risk Factor for Synucleinopathies: A Meta‐Analysis

Movement Disorders, EarlyView.
Abstract Background Variants in GBA1 are important genetic risk factors for synucleinopathies, including Parkinson's disease (PD). Although several GBA1 variants are established risk or severity modifiers, the role of the p.E427K variant remains unclear.
Leah V. Chifamba, Sitki Cem Parlar, Emma N. Somerville, Lang Liu, Eric Yu, Farnaz Asayesh, Jamil Ahmad, Meron Teferra, Jennifer A. Ruskey, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Irina Miliukhina, Lior Greenbaum, Sharon Hassin‐Baer, Orly Goldstein, Mandy Radefeldt, Peter Bauer, Christian Beetz, Allison A. Dilliott, James C. Beck, Konstantin Senkevich, ROPAD Study Group, The Parkinson's Foundation PD GENEration Study, Christine Klein, Roy N. Alcalay, Ziv Gan‐Or   +30 more
wiley   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Impact of Weekly Community-Based Dance Training Over 8 Months on Depression and Blood Oxygen Level–Dependent Signals in the Subcallosal Cingulate Gyrus for People With Parkinson Disease: Observational Study

JMIRx Med
BackgroundDance has emerged as a complementary treatment that may promote adaptive neural plasticity while improving symptoms of Parkinson disease (PD), such as balance, gait, posture, and walking.
Karolina A Bearss, Rebecca E Barnstaple, Rachel J Bar, Joseph F X DeSouza   +3 more
doaj   +1 more source

Dopamine transporter binding in the brain is linked to irritable bowel syndrome in Parkinson's disease

Brain and Behavior, 2023
Background Gastrointestinal symptoms are common in Parkinson's disease (PD), but their neurophysiological correlates are not well understood. We recently reported that functional gastrointestinal symptoms were not associated with asymmetry per se but ...
Kirsi Murtomäki, Juho Joutsa, Tuomas Mertsalmi, Elina Jaakkola, Elina Mäkinen, Reeta Levo, Mikael Eklund, Simo Nuuttila, Eero Pekkonen, Tommi Noponen, Toni Ihalainen, Valtteri Kaasinen, Filip Scheperjans   +12 more
doaj   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Non-motor symptoms in Multiple Sclerosis

Journal of Education, Health and Sport, 2018
Multiple sclerosis (MS) is the most common disease of the brain and spinal cord in young people. European doctors started talking about a new epidemic: multiple sclerosis came out on top among the diseases leading to disability of young people.
Karolina Kubiak, Klaudia Kwiatkowska, Martyna Lamtych, Nataliia Badiuk   +3 more
doaj   +3 more sources

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source