Results 91 to 100 of about 17,995,485 (258)

Bioengineering of the Motor System

open access: yesBioengineering
About fifty years ago, which seems very recent, new technologies for motion analysis were being developed, promising a more detailed and precise study of the human motor system [...]
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Detailed statement of motor vehicle registrations (in dollars)

open access: yes, 2005
Annual; Description based on: 2000; title from caption (viewed Aug.

core  

Loss of mechanical stress induces synovitis, fibrosis and articular cartilage degeneration via distinct synovial cell subsets

open access: yesScientific Reports
Joint function is impaired by disuse, as well as overuse. However, the underlying mechanisms remain unclear. Here, we elucidate the mechanisms of synovial and cartilage changes using a minimized mechanical stress (MMS) mouse model by combining knee joint
Hisatoshi Ishikura   +15 more
doaj   +1 more source

A radiology-based differential diagnostic model for pelvic chondrosarcoma using random forest algorithms

open access: yesFrontiers in Oncology
ObjectiveTo develop a non-invasive diagnostic method for pelvic chondrosarcoma using clinical and radiological features, aiming to improve early diagnostic accuracy and reduce reliance on invasive biopsies.MethodsTwo hundred and thirty-eight patients (39.
Xiao Ma   +16 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Exploring the Bidirectional Relationship Between Numerical Cognition and Motor Performance: A Systematic Review

open access: yesBrain Sciences
Background: Numerical cognition and motor performance rely on overlapping brain systems, yet the extent of their reciprocal interaction remains unclear.
Eliane Rached   +6 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Detailed statement of motor vehicle registrations (in dollars)

open access: yes, 2004
Annual; Description based on: 2000; title from caption (viewed Aug.

core  

Treatment preferences and current practices regarding open tibial shaft fractures

open access: yesFrontiers in Public Health
PurposeThe purpose of this study was to reveal the treatment preferences and current practices regarding open tibial shaft fracture (OTSF).Patients and methodsOnline surveys of treatment preferences and current practice of OTSF were conducted by ...
Shengjun Qian   +19 more
doaj   +1 more source

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