Results 11 to 20 of about 17,995,485 (258)

Pathomechanism of intervertebral disc degeneration

JOR Spine, 2020
Intervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting ...
Takeshi Oichi, Yuki Taniguchi, Yasushi Oshima, Sakae Tanaka, Taku Saito   +4 more
doaj   +1 more source

Application of Physical Function Model to State Estimations of Nonlinear Mechanical Systems

IEEE Access, 2021
The physical function model has been effectively used for model-based development (MBD) of automobile systems. This research demonstrates a novel application of this modeling method to the state estimation of nonlinear mechanical systems based on the ...
Heisei Yonezawa, Itsuro Kajiwara, Shota Sato, Chiaki Nishidome, Takashi Hatano, Shigeki Hiramatsu   +5 more
doaj   +1 more source

Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS

Frontiers in Pharmacology, 2022
Osteoarthritis (OA) is one of the most common chronic musculoskeletal disorder worldwide, representing a major source of disability, pain and socioeconomic burden.
Changjian Lin, Changjian Lin, Changjian Lin, Changjian Lin, Lujie Ge, Lujie Ge, Lujie Ge, Lujie Ge, Luping Tang, Yuzhe He, Yuzhe He, Yuzhe He, Yuzhe He, Safwat Adel Abdo Moqbel, Safwat Adel Abdo Moqbel, Safwat Adel Abdo Moqbel, Safwat Adel Abdo Moqbel, Kai Xu, Kai Xu, Kai Xu, Kai Xu, Diana Ma, Diana Ma, Diana Ma, Diana Ma, Xing Zhou, Xing Zhou, Xing Zhou, Xing Zhou, Jisheng Ran, Jisheng Ran, Jisheng Ran, Jisheng Ran, Lidong Wu, Lidong Wu, Lidong Wu, Lidong Wu   +36 more
doaj   +1 more source

Cervical single open-door laminoplasty with or without local lateral mass screw fixation and fusion to treat cervical spinal cord injuries accompanied by segmental spinal canal stenosis

Frontiers in Surgery, 2023
Study DesignRetrospective.ObjectivesTo investigate the efficacy of cervical single open-door laminoplasty with and without local lateral mass screw fixation and fusion as treatments for cervical spinal cord injuries accompanied by multisegmental spinal ...
Zihao Yu, Zihao Yu, Zihao Yu, Zihao Yu, Hongwei Xie, Hongwei Xie, Hongwei Xie, Hongwei Xie, Ziyu Ouyang, Ziyu Ouyang, Ziyu Ouyang, Ziyu Ouyang, Hua Zhang, Hua Zhang, Hua Zhang, Hua Zhang   +15 more
doaj   +1 more source

Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

Nature Communications, 2016
Rela is a transcription factor shown to have seemingly contradictory roles in anabolism and catabolism of cartilage. Here the authors find that Rela prevents chondrocyte apoptosis and that homozygous knockout causes accelerated osteoarthritis in adults ...
Hiroshi Kobayashi, Song Ho Chang, Daisuke Mori, Shozo Itoh, Makoto Hirata, Yoko Hosaka, Yuki Taniguchi, Keita Okada, Yoshifumi Mori, Fumiko Yano, Ung-il Chung, Haruhiko Akiyama, Hiroshi Kawaguchi, Sakae Tanaka, Taku Saito   +14 more
doaj   +1 more source

Experimental study on oil-air multiphase flow in a right circular cylindrical channel during reciprocating motion

Journal of Fluid Science and Technology, 2019
Much attention has recently been given to high-efficiency cooling of pistons in internal combustion engines by cooling channels because of improved thermal efficiency. Cooling a piston efficiently requires a grasp of the gas-liquid multiphase flow state.
Akira NAKASHIMA, Goichi NITTA, Keiya NISHIDA, Hitoshi HONGOU, Hideaki YOKOHATA, Yoichi OGATA   +5 more
doaj   +1 more source

Vibration control of automotive drive system with backlash considering control period constraint

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
This paper proposes a vibration control method of an automotive drive system with backlash to maintain stability and control performance under the control period constraint due to an engine's characteristics.
Heisei YONEZAWA, Itsuro KAJIWARA, Chiaki NISHIDOME, Shigeki HIRAMATSU, Masato SAKATA, Takashi HATANO   +5 more
doaj   +1 more source

An experimental investigation of the behavior of oil jets injected by a 90° curved circular nozzle

Journal of Fluid Science and Technology, 2018
The high efficiency cooling of pistons in internal combustion engines by oil jets has recently received widespread attention. To date, curved circular oil jet nozzles have been commonly employed.
Akira NAKASHIMA, Goichi NITTA, Keiya NISHIDA, Hitoshi HONGOU, Hideaki YOKOHATA, Yoichi OGATA   +5 more
doaj   +1 more source

Transient numerical fluid analysis on gas distribution to anode cells of a fuel cell stack under start-up condition

Nihon Kikai Gakkai ronbunshu, 2015
Catalyst degradation on both the anode and cathode sides is one of the most critical problems caused by lack of hydrogen in each channel in the active area of a polymer electrolyte fuel cell.
Yasushi ICHIKAWA, Nobuyuki OSHIMA, Yuichiro TABUCHI   +2 more
doaj   +1 more source

RETRACTED: Bioinformatics analysis based on crucial genes of endothelial cells in rheumatoid

Frontiers in Genetics, 2023
Objectives: Synovial neovascularization is an early and remarkable event that promotes the development of rheumatoid arthritis (RA) synovial hyperplasia.
Xing Zhou, Xing Zhou, Xing Zhou, Xing Zhou, Lidong Wu, Lidong Wu, Lidong Wu, Lidong Wu   +7 more
doaj   +1 more source