Results 151 to 160 of about 4,518,026 (355)
Probing the Influence of Paternal Diet on Offspring Neuroanatomy With Mouse MRI
Brain and BehaviorPurpose Previous studies have established that parental consumption of a diet high in fat and simple sugar (HF/HSS) leads to long‐term effects on offspring brain development.
Emma G. W. McKnight +7 more
doaj +1 more source
Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain
, 2008 Giovanni Lugli +3 more
openalex +2 more sources
Defective myelination in an RNA polymerase III mutant leukodystrophic mouse
, 2021 Emilio Merheb +7 more
openalex +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy
, 2017 Leonela Amoasii +12 more
openalex +1 more source
Endogenous N-Acetylaspartylglutamate (NAAG) Inhibits Synaptic Plasticity/Transmission in the Amygdala in a Mouse Inflammatory Pain Model [PDF]
, 2010 Mary Oluwakemi. Adedoyin +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Simple Method of Isolating Mouse Aortic Endothelial Cells
, 2005 Mika Kobayashi +4 more
openalex +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Vivo-Morpholinos: A Non-Peptide Transporter Delivers Morpholinos into a Wide Array of Mouse Tissues
, 2008 Paul A. Morcos, Yongfu Li, Shan Jiang
openalex +1 more source