Results 61 to 70 of about 3,039,643 (308)

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology [PDF]

open access: yes, 2017
Plants and many lower organisms, but not mammals, express alternative oxidases (AOXs) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping.
Eric Dufour   +68 more
core   +1 more source

A mouse with history [PDF]

open access: yesNature Reviews Genetics, 2020
A new study in Cell describes the CRISPR array repair lineage tracing (CARLIN) engineered mouse line that genomically encodes all the components for CRISPR-based lineage tracking at single-cell resolution.
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The orienting mouse: An input device with attitude [PDF]

open access: yes, 2013
This paper presents a modified computer mouse, the Orienting Mouse, which delivers orientation as an additional dimension of input; when the mouse is moved on a flat surface it reports, in addition to the conventional x, y translation, angular rotation ...
Rogers, Bill, Apperley, Mark
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Mouse-X

open access: yes, 2014
Mouse-X is a short Science Fiction film completed in 2014. It explores identity and reality through a powerful short story about a man trapped in a building with a thousand clones of himself, begging the question, 'Who are you, if you're not the only you?
Justin Tagg (17168326)
core   +1 more source

Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva [PDF]

open access: yes, 2010
The genetic background of a patient determines in part if a person develops a mild form of malaria and recovers, or develops a severe form and dies. We have used a mouse model to detect genes involved in the resistance or susceptibility to Plasmodium ...
Winzeler, E.A.   +43 more
core   +2 more sources

Joseph the MoUSE — Mouse Ultrasonic Sound Explorer

open access: yesSoftwareX
Joseph the MoUSE — Mouse Ultrasonic Sound Explorer (MoUSE) software aims to address the issue of manual analysis of recordings from experiments on rodents by introducing automatic techniques for ultrasonic vocalization (USV) detection. It combines deep learning (DL) methods with classical pattern recognition and computer graphics algorithms.
Adam Kania   +5 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

International Mouse Phenotyping Consortium IMPC. Behavior and Sensory WG

open access: yes, 2023
IMPC-Behavior and Sensory WG overview, pipeline. Challenges. Behavioral procedures, number of mouse lines and WG publications. Schizophrenia-associated genes. Genes involved in anxiety behavior.
Sabine Hoelter   +2 more
core  

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