Results 41 to 50 of about 2,175,037 (261)

Joseph the MoUSE — Mouse Ultrasonic Sound Explorer

open access: yesSoftwareX
Joseph the MoUSE — Mouse Ultrasonic Sound Explorer (MoUSE) software aims to address the issue of manual analysis of recordings from experiments on rodents by introducing automatic techniques for ultrasonic vocalization (USV) detection. It combines deep learning (DL) methods with classical pattern recognition and computer graphics algorithms.
Adam Kania   +5 more
openaire   +4 more sources

The mouse that trolled [PDF]

open access: yesJournal of Law and the Biosciences, 2015
As one of the actors in the mouse trolling drama detailed in Bubela, Vishnubhakat and Cook-Deegan (2015),1 I might say that, although I was not aware of this or contacted by the authors before publication, I am in complete agreement with their paper and its conclusions.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Acetylated tubulin is essential for touch sensation in mice

open access: yeseLife, 2016
At its most fundamental level, touch sensation requires the translation of mechanical energy into mechanosensitive ion channel opening, thereby generating electro-chemical signals.
Shane J Morley   +24 more
doaj   +1 more source

Multiple-mouse magnetic resonance imaging with cryogenic radiofrequency probes for evaluation of brain development

open access: yesNeuroImage, 2022
Multiple-mouse magnetic resonance imaging (MRI) increases scan throughput by imaging several mice simultaneously in the same magnet bore, enabling multiple images to be obtained in the same time as a single scan.
A. Arbabi   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Hypothalamic regulation of sepsis-associated anorexia: cytokine and hormonal signalling through AgRP/POMC circuits

open access: yesEMBO Molecular Medicine
Sepsis is a life-threatening syndrome resulting from a dysregulated host response to an infection and is considered as a major global health priority.
Wanting Zhu   +2 more
doaj   +1 more source

Effect of Shipping on the Microbiome of Donor Mice Used to Reconstitute Germ-Free Recipients

open access: yesGut Microbes Reports
The gut microbiome (GM) influences multiple processes during host development and maintenance. To study these events, fecal microbiota transfer (FMT) to germ-free (GF) recipients is often performed.
Zachary L. McAdams   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy