Results 171 to 180 of about 96,662 (219)

Biology of mouse mammary tumor virus (MMTV)

Cancer Letters, 1995
Mouse mammary tumor viruses (MMTV) replicate in the mammary gland, appear as infectious particles in mother's milk and invade the sucking pups from the intestinal tract. The immune system is essential for MMTV in the gut to reach the mammary gland. These properties make the life cycle of MMTV unique.
A, Matsuzawa, H, Nakano, T, Yoshimoto, K, Sayama   +3 more
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Identification of mouse mammary tumor virus-specific mRNA

Journal of Virology, 1979
Complementary DNA corresponding to the RNA genome of mouse mammary tumor virus was used to identify viral RNA contained in polysomes of a virus-producing mammary tumor cell line. Separation of polysomal mRNA by agarose gel electrophoresis, transfer of the RNA to diazobenzyloxymethyl paper, and hybridization with 32P-labeled mouse mammary tumor virus ...
Groner, B, Hynes, N E, Diggelmann, H
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Breast Cancer and Mouse Mammary Tumor Virus

Annals of Internal Medicine, 1983
Excerpt To the editor: The recent report by Poon and associates (1) provides additional evidence associating antigens of mouse mammary tumor virus with human breast cancer.
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The polypeptide composition of mouse mammary tumor virus

Virology, 1974
Abstract The polypeptide composition of mouse mammary tumor virus isolated from several strains of mice, has been examined by polyacrylamide gel electrophoresis. Gel Patterns, as revealed by staining and 14 C amino acid labelling, showed 10 polypeptide species reproducibly associated with the virus.
C, Dickson, J J, Skehel
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Sandwich enzyme immunoassay of mouse mammary tumor virus

Experientia, 1981
A highly sensitive sandwich enzyme immunoassay for the mouse mammary tumor virus (MMTV) is described. The assay can detect 3 ng/ml of MMTV. The enzyme used is s-D-galactosidase fromEscherichia coli and the solid phase used is a piece of silicon rubber.
M, Takahashi, S, Saga, S, Nagayoshi, M, Imai, Y, Tsutsui, K, Kato, M, Hoshino   +6 more
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Quantification of mouse mammary tumor virus structural proteins in hormone‐induced mammary tumors of low mammary tumor mouse strains

International Journal of Cancer, 1980
AbstractThe expression of the mouse mammary tumor virus (MMTV) in hormone‐induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinity‐ and ion‐exchange chromatography columns. The purified viral proteins were electrophoretically homogeneous and retained
Nusse, R, Michalides, R, Boot, L M, Ropcke, G   +3 more
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Mouse mammary tumor virus and mammary tumorigenesis in wild mice

Pathology International, 1996
The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV.
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Involvement of mouse mammary tumor virus in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains

Journal of Virology, 1978
The involvement of the mouse mammary tumor virus (MTV) in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains was studied by comparing the amounts of MTV RNA and MTV DNA sequences in mammary tumors and other tissues of mice with an without hormonal treatments. The following results were obtained.
Michalides, R, Deemter, L V, Nusse, R, Ropcke, G, Boot, L   +4 more
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Mouse Mammary Tumor Virus and the Immune System

Immunologic Research, 2003
Mouse mammary tumor virus (MMTV) is a nonacute transforming retrovirus that causes mammary tumors in susceptible strains of mice. Upon milk-borne transmission, B cells in the gut become infected and subsequently present a virus-encoded superantigen to cognate T cells.
Jennifer, Czarneski, John C, Rassa, Susan R, Ross   +2 more
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Immune response to mouse mammary tumor virus

Current Opinion in Immunology, 1996
Superantigens of mouse mammary tumor virus induce a strong cognate interaction between T cells and B cells. In addition to amplifying the virus-infected B-cell pool, this superantigen-driven interaction leads to the differentiation of virus-specific B cells into plasma cells. Successful interaction between T cells and B cells is required for completion
S A, Luther, H, Acha-Orbea
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