Results 181 to 190 of about 63,529 (225)

The polypeptide composition of mouse mammary tumor virus

Virology, 1974
Abstract The polypeptide composition of mouse mammary tumor virus isolated from several strains of mice, has been examined by polyacrylamide gel electrophoresis. Gel Patterns, as revealed by staining and 14 C amino acid labelling, showed 10 polypeptide species reproducibly associated with the virus.
C, Dickson, J J, Skehel
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Biology of mouse mammary tumor virus (MMTV)

Cancer Letters, 1995
Mouse mammary tumor viruses (MMTV) replicate in the mammary gland, appear as infectious particles in mother's milk and invade the sucking pups from the intestinal tract. The immune system is essential for MMTV in the gut to reach the mammary gland. These properties make the life cycle of MMTV unique.
A, Matsuzawa, H, Nakano, T, Yoshimoto, K, Sayama   +3 more
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Surface structure of mouse mammary tumor virus

Virology, 1974
Abstract The structure of the envelope of mouse mammary tumor virus (MuMTV) was studied by using negative stain, thin sections and freeze-drying-shadowing. The surface of the viral membrane was found to contain a reticular structure composed mainly of hexagons and occasional pentagons. The spacing between the nearest corners was about 74 A. The viral
Sarkar, N H, Moore, D H
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Involvement of mouse mammary tumor virus in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains

Journal of Virology, 1978
The involvement of the mouse mammary tumor virus (MTV) in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains was studied by comparing the amounts of MTV RNA and MTV DNA sequences in mammary tumors and other tissues of mice with an without hormonal treatments. The following results were obtained.
Michalides, R, Deemter, L V, Nusse, R, Ropcke, G, Boot, L   +4 more
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Selective amplification of mouse mammary tumor virus in mammary tumors of GR mice

Journal of Virology, 1980
DNAs extracted from the mammary tumors of GR mice were analyzed for mouse mammary tumor virus proviral sequences by the restriction enzyme-Southern blot procedure. The tumor DNAs contain more proviral copies of mouse mammary tumor virus than DNA from a nonmalignant tissue. The degree of proviral amplification is small (ca. one to five additional copies)
T G, Fanning, J P, Puma, R D, Cardiff
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Breast Cancer and Mouse Mammary Tumor Virus

Annals of Internal Medicine, 1983
Excerpt To the editor: The recent report by Poon and associates (1) provides additional evidence associating antigens of mouse mammary tumor virus with human breast cancer.
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Quantification of mouse mammary tumor virus structural proteins in hormone‐induced mammary tumors of low mammary tumor mouse strains

International Journal of Cancer, 1980
AbstractThe expression of the mouse mammary tumor virus (MMTV) in hormone‐induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinity‐ and ion‐exchange chromatography columns. The purified viral proteins were electrophoretically homogeneous and retained
Nusse, R, Michalides, R, Boot, L M, Ropcke, G   +3 more
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Gene order of the mouse mammary tumor virus glycoproteins

Virology, 1977
Immunochemical and tryptic peptide mapping techniques were used to show that the mouse mammary tumor virus (MMTV) envelope glycoproteins gp52 and gp36 are distinct components derived from a common glycosylated precursor polypeptide of 75,000 daltons (gPr75). Because both gp52 and gp36 are derived from a common precursor polypeptide and therefore have a
G, Schochetman, S, Oroszlan, L, Arthur, D, Fine   +3 more
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Mouse mammary tumor virus as a model for viral carcinogenesis

Journal of Toxicology and Environmental Health, 1976
Evidence is presented suggesting that genetic control may be the limiting factor in mammary tumor virus (MTV) positive mammary oncogenesis. Studies with hybrid mice involving high and low MTV-expressing murine strains suggest that expression of MTV in milk may not be as important in tumorigenesis as previously thought.
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Mouse Mammary Tumor Virus and Cancer

2011
The retrovirus mouse mammary tumor virus (MMTV) was discovered in the 1930s as a milk-transmitted agent that causes breast cancer in mice. MMTV causes mammary tumors by insertional activation or mutation of cellular oncogenes. Some of the oncogenes activated by MMTV insertion have been also associated with human breast cancer.
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