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2021
The intravenous challenge model of Candida albicans infection in mice is a well-established procedure that mirrors disseminated candidiasis in humans. In this model, in which the fungus is delivered into the bloodstream causing a systemic infection, the kidneys are the primary target organs.
Pilar, Fajardo +2 more
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The intravenous challenge model of Candida albicans infection in mice is a well-established procedure that mirrors disseminated candidiasis in humans. In this model, in which the fungus is delivered into the bloodstream causing a systemic infection, the kidneys are the primary target organs.
Pilar, Fajardo +2 more
openaire +2 more sources
Mouse Models of Atherosclerosis
Current Protocols in Immunology, 2012AbstractGenetically altered mice carrying mutations of genes encoding crucial components of the immune system and lipid metabolism have been widely used to study the role of immune responses and inflammation in atherosclerosis. These mice are often fed a diet, with a high content of cholesterol and saturated fat in order to induce hypercholesterolemia ...
E, Maganto-Garcia +2 more
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Journal of Clinical Neuroscience, 2015
Gliomas are the most common primary tumour in the central nervous system in adults. The pathological hallmark of gliomas is their propensity for extensive infiltration into the surrounding brain parenchyma which results in tumour recurrence. Despite the use of optimal surgical removal and adjuvant therapies the most aggressive of these tumours ...
Stanley S. Stylli +4 more
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Gliomas are the most common primary tumour in the central nervous system in adults. The pathological hallmark of gliomas is their propensity for extensive infiltration into the surrounding brain parenchyma which results in tumour recurrence. Despite the use of optimal surgical removal and adjuvant therapies the most aggressive of these tumours ...
Stanley S. Stylli +4 more
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2013
The generation of transgenic mouse models has been a powerful technique for several decades and is still widely used. There have been many manuals and general reviews of this technology. This chapter is designed to be a "how-to" resource with detailed specifics.
Jennifer, Skelton +3 more
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The generation of transgenic mouse models has been a powerful technique for several decades and is still widely used. There have been many manuals and general reviews of this technology. This chapter is designed to be a "how-to" resource with detailed specifics.
Jennifer, Skelton +3 more
openaire +2 more sources
Mouse Models of Phaeohyphomycosis
2023Infections by dematiaceous fungi especially phaeohyphomycosis are an emerging group of infectious diseases worldwide with a variety of clinical presentations. The mouse model is a useful tool for studying phaeohyphomycosis, which can mimic dematiaceous fungal infections in humans.
Yi, Zhang, Ruoyu, Li
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Current Protocols in Microbiology, 2009
AbstractA major challenge in influenza research is the selection of an appropriate animal model that accurately reflects the disease and protective immune response to influenza infection in humans. Ferrets are exquisitely susceptible to infection with human influenza viruses and are widely believed to be the ideal small animal model for influenza ...
Yumiko, Matsuoka +2 more
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AbstractA major challenge in influenza research is the selection of an appropriate animal model that accurately reflects the disease and protective immune response to influenza infection in humans. Ferrets are exquisitely susceptible to infection with human influenza viruses and are widely believed to be the ideal small animal model for influenza ...
Yumiko, Matsuoka +2 more
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Modern Drama, 1969
IN EDWARD ALBEE'S Tiny Alice QUALITIES PROMINENT IN Who's Afraid of Virginia Woolf? are heightened further: cruelty, concern with reality and illusion, and an undertone that seems allegorical but that refuses to yield a meaning. These qualities present a problem, because if a play seems allegorical, yet its sense remains hidden as we look for a motive
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IN EDWARD ALBEE'S Tiny Alice QUALITIES PROMINENT IN Who's Afraid of Virginia Woolf? are heightened further: cruelty, concern with reality and illusion, and an undertone that seems allegorical but that refuses to yield a meaning. These qualities present a problem, because if a play seems allegorical, yet its sense remains hidden as we look for a motive
openaire +1 more source