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MondoA Is Required for Normal Myogenesis and Regulation of the Skeletal Muscle Glycogen Content in Mice [PDF]
Diabetes & Metabolism Journal, 2021 Background Skeletal muscle is the largest tissue in the human body, and it plays a major role in exerting force and maintaining metabolism homeostasis.
Hui Ran +7 more
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Approaches for timeline reductions in pathogenesis studies using genetically modified mice
Microbiology Spectrum, 2023 Although genetically modified mouse models have long been a powerful tool for microbiology research, the manipulation of the mouse genome is expensive, time consuming, and has historically remained the domain of dedicated animal facilities.
Samantha Skavicus, Nicholas S. Heaton
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Targeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertility [PDF]
Genetics and Molecular Biology, 2014 The mouse testis-enriched Znf230 gene, which encodes a type of RING finger protein, is present primarily in the nuclei of spermatogonia, the acrosome and the tail of spermatozoa.
Yunqiang Liu +5 more
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Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice. [PDF]
PLoS ONE, 2013 The p21-activated kinases are effector proteins for Rho-family GTPases. PAK4, PAK5, and PAK6 are the group II PAKs associated with neurite outgrowth, filopodia formation, and cell survival.
Melody A Furnari +4 more
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Sleep in Kcna2 knockout mice [PDF]
BMC Biology, 2007 Abstract Background Shaker codes for a Drosophila voltage-dependent potassium channel. Flies carrying Shaker null or hypomorphic mutations sleep 3–4 h/day instead of 8–14 h/day as their wild-type siblings do. Shaker-like channels are conserved across species but it is unknown whether they affect sleep
Douglas, CL +6 more
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Rapid Way to Generate Mouse Models for In Vivo Studies of the Endothelium
Journal of Lipid and Atherosclerosis, 2021 A single layer of squamous endothelial cells (ECs), the endothelium, regulates the flow of substance and fluid into and out of a tissue. The endothelium is also involved in vasculogenesis, the formation of new blood vessels, which is a crucial process ...
Ho Lee
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