Results 171 to 180 of about 38,779 (193)

Mouse Model of Cervicovaginal Papillomavirus Infection

2014
Virtually all cervical cancers are caused by human papillomavirus infections. The efficient assembly of pseudovirus (PsV) particles incorporating a plasmid expressing a reporter gene has been an invaluable tool in the development of in vitro neutralization assays and in studies of the early mechanisms of viral entry in vitro.
Nicolas, Çuburu, Rebecca J, Cerio, Cynthia D, Thompson, Patricia M, Day   +3 more
openaire   +2 more sources

Virus-specific transcription in bovine papillomavirus-transformed mouse cells

Virology, 1982
Abstract We have characterized the viral-specific RNAs present in C127 mouse cells transformed by the BPV-1 virus or by cloned DNA. Five distinct BPV-1 polyadenylated RNA species can be detected by size fractionation on denaturing formaldehyde agarose gels, measuring 1050, 1150, 1700, 3800, and 4050 bases.
C A, Heilman, L, Engel, D R, Lowy, P M, Howley   +3 more
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Papillomavirus L1 capsids agglutinate mouse erythrocytes through a proteinaceous receptor

Journal of Virology, 1995
Virus-like particles (VLPs) composed of L1 derived from bovine papillomavirus type 1 (BPV-1), several human papillomavirus types, or cottontail rabbit papillomavirus (CRPV) agglutinated mouse but not human or rat erythrocytes. Treatment of mouse erythrocytes with trypsin prevented hemagglutination (HA) by BPV-1.
R B, Roden, N L, Hubbert, R, Kirnbauer, F, Breitburd, D R, Lowy, J T, Schiller   +5 more
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A Mouse Fibroblast Cell Model to Study Human Papillomavirus-Associated Tumorigenesis

Biochemical and Biophysical Research Communications, 2000
Cervical cancer represents the second most common cancer in women worldwide. About 90% of cervical cancer contain high-risk human papillomavirus (HPV) DNA, most often HPV type 16. Animal models and mostly laboratory mice are excellent for carrying out diverse immunological studies.
P, Hernández, N, Merino, O, Lopez-Ocejo, M J, Araña   +3 more
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Tumorigenicity and H-2 expression of papillomavirus-transformed mouse cell lines

Cancer Immunology Immunotherapy, 1990
Tumorigenicity in immunocompetent syngeneic mice and H-2 class I antigen expression of BPV1-transformed mouse cell lines had no correlation. H-2 expression was examined using monoclonal anti-(H-2Kb) and anti-(H-2Db) antibodies in immunofluorescence staining for flow cytometry analysis and by determining the sensitivity of the cells to cytolysis by ...
A, Laatikainen, H, Karjalainen, H, Jägerroos, H, Sarkkinen, R, Mäntyjärvi   +4 more
openaire   +2 more sources

Integration and transcription of human papillomavirus type 6 recombinant DNA in mouse cells

Virus Research, 1987
Human papillomavirus (HPV) DNA is found in nature mostly in an episomal form. However, in permanent cell lines established from cervical carcinomas in which HPV sequences are present, they are usually integrated in the host genome. In vitro studies of HPV have been hampered because of the difficulty of stably maintaining HPV sequences in transfected ...
S, Mitrani-Rosenbaum, N, Kitron
openaire   +2 more sources

Structure of bovine papillomavirus type 1 DNA in a transformed mouse cell line

Journal of Molecular Biology, 1986
Linearized bovine papillomavirus type 1 (BPV-1) DNA was introduced into mouse C127 cells, where it recircularized and replicated as an intact monomeric, extrachromosomal circular form in the resulting transformants. These cells contained a mixture of complex high molecular weight forms that were converted to a linear form of approximately BPV-1 size ...
R C, Allshire, C J, Bostock
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Papillomavirus Infection, Skin, Mouse

1989
Adult European harvest mice (Micromys minutis) develop raised, firm, often hyperpigmented, verrucous masses on the haired skin, tail, and mucocutaneous junctions of the mouth (Fig.216) and anus (Sundberg et al. 1987). The tumors are often round and less than 0.5 cm in diameter.
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Introduction of cloned human papillomavirus genomes into mouse cells and expression at the RNA level

Virology, 1983
The entire DNA genomes of five different human papillomaviruses (HPVs) were cloned into the BamHI site of pBR322 (HPV-1a, HPV-3, HPV-4, and HPV-9) or the EcoRI site of pBR325 (HPV-2), using as starting materials virus preparations isolated from papillomas of individual patients.
K H, Brackmann, M, Green, W S, Wold, A, Rankin, P M, Loewenstein, M A, Cartas, P R, Sanders, K, Olson, G, Orth, S, Jablonska, D, Kremsdorf, M, Favre   +11 more
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Transformation of C127 mouse fibroblasts by human papillomavirus 16.

Cancer research, 1988
We have compared the ability of cloned DNAs of HPV16, a human papillomavirus associated with cervical carcinoma, and BPV1, a papillomavirus inducing skin lesions in cattle, to transform murine C127 cells. Unlike BPV1, HPV16 DNA failed to induce foci when C127 cells were transfected and maintained as monolayers; HPV16-transformed C127 cells could only ...
D, Morgan, G, Pecoraro, I, Rosenberg, V, Defendi   +3 more
openaire   +1 more source